Results 71 to 80 of about 197,033 (249)

Human induced pluripotent stem cell-derived atrial cardiomyocytes carrying an SCN5A mutation identify nitric oxide signaling as a mediator of atrial fibrillation [PDF]

, 2021
Liang Hong, Meihong Zhang, Olivia T Ly, Hanna Chen, Arvind Sridhar, Erin Lambers, Brandon Chalazan, Seock‐Won Youn, Mark Maienschein‐Cline, Leonid Feferman, Sang‐Ging Ong, Joseph C. Wu, Jalees Rehman, Dawood Darbar   +13 more
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A Human Gonadal Cell Model From Induced Pluripotent Stem Cells [PDF]

Frontiers in Genetics, 2018
Las células de Sertoli son los principales actores en el desarrollo de las gónadas masculinas y su estudio puede arrojar luz sobre los trastornos 46,XY del desarrollo sexual. Las células de Sertoli primarias maduras son incapaces de proliferar en cultivos in vitro prolongados y los modelos de células de Sertoli disponibles tienen varias limitaciones ...
Daniel Rodríguez Gutiérrez, Wassim Eid, Wassim Eid, Anna Biason-Lauber   +3 more
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Establishment and characterization of induced pluripotent stem cells from placental mesenchymal stromal cells

Stem Cell Research, 2018
Human term placenta is a bulky organ which harbours abundant mesenchymal stromal cells. This study reports isolation and characterization of placental mesenchymal stromal cells (PMSCs) followed by reprogramming of PMSCs to induced pluripotent stem cells (
Shagufta Parveen
doaj   +1 more source

Induced pluripotent stem cells, a giant leap for mankind therapeutic applications [PDF]

, 2019
Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging.
Bragança, José, Lopes, João A. P., Santos, João, Silva, Leonardo   +3 more
core   +1 more source

Modeling Leukemia with Human Induced Pluripotent Stem Cells [PDF]

Cold Spring Harbor Perspectives in Medicine, 2019
The reprogramming of human somatic cells into induced pluripotent stem cells (iPSCs) a little over a decade ago raised exciting prospects to transform the study and potentially also the therapy of human diseases. iPSC models have now been created for a multitude of hematologic diseases, including malignancies.
openaire   +2 more sources

Cell Therapy for Type 1 Diabetes [PDF]

, 2014
Acknowledgements The work described in this review was supported by a grant from the MRC. K.R.M. is supported by a fellowship from the Scottish Translational Medicines and Therapeutics Initiative through the Wellcome Trust.Peer reviewedPublisher ...
Docherty, H. M., Docherty, K., Lima, M. J., Muir, K. R.   +3 more
core   +1 more source

Lower Oncogenic Potential of Human Mesenchymal Stem Cells Derived from Cord Blood Compared to Induced Pluripotent Stem Cells

International Journal of Organ Transplantation Medicine, 2015
Background: In regenerative medicine, use of each of the mesenchymal stem cells derived from bone marrow, cord blood, and adipose tissue, has several cons and pros.
T Foroutan, M Najmi, N Kazemi, M Hasanlou, A Pedram   +4 more
doaj  

Modeling Treatment Response for Lamin A/C Related Dilated Cardiomyopathy in Human Induced Pluripotent Stem Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundPrecision medicine is an emerging approach to disease treatment and prevention that takes into account individual variability in the environment, lifestyle, and genetic makeup of patients.
Yee‐Ki Lee, Yee‐Man Lau, Zhu‐Jun Cai, Wing‐Hon Lai, Lai‐Yung Wong, Hung‐Fat Tse, Kwong‐Man Ng, Chung‐Wah Siu   +7 more
doaj   +1 more source

Induced pluripotent stem cell-derived lung alveolar epithelial type II cells reduce damage in bleomycin-induced lung fibrosis

Stem Cell Research & Therapy, 2020
Background Idiopathic pulmonary fibrosis is a chronic, progressive, and severe disease with a limited response to currently available therapies. Epithelial cell injury and failure of appropriate healing or regeneration are central to the pathogenesis of ...
Belén Alvarez-Palomo, Luis Ignacio Sanchez-Lopez, Yuben Moodley, Michael J. Edel, Anna Serrano-Mollar   +4 more
doaj   +1 more source

A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss [PDF]

, 2021
Azel Zine, Yassine Messat, Bernd Fritzsch   +2 more
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