Results 81 to 90 of about 197,033 (249)

Big bottlenecks in cardiovascular tissue engineering. [PDF]

, 2018
Although tissue engineering using human-induced pluripotent stem cells is a promising approach for treatment of cardiovascular diseases, some limiting factors include the survival, electrical integration, maturity, scalability, and immune response of ...
Abilez, Oscar J, Huang, Ngan F, Morris, Viola B, Nakayama, Karina H, Pardon, Gaspard, Pruitt, Beth L, Sayed, Nazish, Serpooshan, Vahid, Wu, Joseph C, Wu, Sean M, Yoon, Young-Sup, Zhang, Jianyi   +11 more
core  

3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells [PDF]

, 2019
Bioprinting techniques use bioinks made of biocompatible non-living materials and cells to build 3D constructs in a controlled manner and with micrometric resolution.
Benedetti, Maria Cristina, Brighi, Carlo, Colosi, Cristina, Di Angelantonio, Silvia, Ghirga, Silvia, Rosa, Alessandro, Rosito, Maria, Salaris, Federico, Soloperto, Alessandro, Turris, Valeria de   +9 more
core   +1 more source

Complete Meiosis from Human Induced Pluripotent Stem Cells

Stem Cells, 2011
Abstract Gamete failure-derived infertility affects millions of people worldwide; for many patients, gamete donation by unrelated donors is the only available treatment. Embryonic stem cells (ESCs) can differentiate in vitro into germ-like cells, but they are genetically unrelated to the patient.
C, Eguizabal, N, Montserrat, R, Vassena, M, Barragan, E, Garreta, L, Garcia-Quevedo, F, Vidal, A, Giorgetti, A, Veiga, J C, Izpisua Belmonte   +9 more
openaire   +2 more sources

Generation of an induced pluripotent stem cell line SYSUi-004-A from a child of microcephaly with TYW1 mutations

Stem Cell Research, 2020
We generated an induced human pluripotent stem cell line from a child with microcephaly carrying compound heterozygous mutations of TYW1 inherited from healthy parents.
Chuanbo Sun, Pei Zhou, Simin Yuan, Ruirui Guo, Zhan Zhang, Qingyang Xu, Dingding Han, Lu He, Hongmei Tang, Kaishou Xu, Hao Hu, Na Li   +11 more
doaj   +1 more source

Induced pluripotent stem cells: ex vivo models for human diseases due to mitochondrial DNA mutations [PDF]

, 2023
Chao Chen, Min‐Xin Guan
openalex   +1 more source

A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]

, 2018
open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...

core   +1 more source

Cell fiber-based three-dimensional culture system for highly efficient expansion of human induced pluripotent stem cells

Scientific Reports, 2017
Human pluripotent stem cells are a potentially powerful cellular resource for application in regenerative medicine. Because such applications require large numbers of human pluripotent stem cell-derived cells, a scalable culture system of human ...
Kazuhiro Ikeda, Shogo Nagata, Teru Okitsu, Shoji Takeuchi   +3 more
doaj   +1 more source

Stem cell therapy for spinal cord injury: The use of oligodendrocytes and motor neurons derived from human embryonic stem cells

Translational Research in Anatomy, 2015
Over the past few years, the understanding of stem cells as a potential therapeutic source has significantly evolved, and the previous concept of irreparable neural injury is being reconsidered.
Nimer Adeeb, Aman Deep, Nicole Hose, Mona Rezaei, Salman Abbasi Fard, R. Shane Tubbs, Parham Yashar, Mark A. Liker, Babak Kateb, Martin M. Mortazavi   +9 more
doaj   +1 more source

Differentiation of definitive endoderm from human induced pluripotent stem cells on hMSCs feeder in a defined medium [PDF]

, 2016
Background: The Definitive Endoderm (DE) differentiation using the undefined media and non-human feeders can cause contaminations in the generated cells for therapeutic applications.
Geramizadeh, B., Hosseinkhani, S., Jaafarpour, Z., Karimi, M.H., Mobarra, N., Soleimani, M., Yaghmaei, P.   +6 more
core  

Transcription Factor-Mediated Generation of Dopaminergic Neurons from Human iPSCs—A Comparison of Methods

Cells
Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been generated
Kirstin O. McDonald, Nikita M. A. Lyons, Luca K. C. Gray, Janet B. Xu, Lucia Schoderboeck, Stephanie M. Hughes, Indranil Basak   +6 more
doaj   +1 more source