Results 211 to 220 of about 119,573 (312)

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Upcycling of Citrus Waste by Natural Deep Eutectic Solvents: Green Extraction of Bioactive Compounds with Antioxidant and Regenerative Properties on Human Keratinocytes. [PDF]

Nutrients
Silla A, Punzo A, Comito R, Porru E, Gozzi G, Barbalace MC, Perillo M, Lorenzini A, Malaguti M, Hrelia S, Caliceti C.   +10 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Response of murine fibroblasts or human keratinocytes to micro- and nano-scale titanium particles: the permeability of particles across keratinocytes' monolayers. [PDF]

Clin Oral Investig
Pacheco C, Messous R, Moura RP, Almeida A, Silva P, Sarmento B, Bousbaa H, Souza JCM.   +7 more
europepmc   +1 more source

A Large Pigmented Lesion on the Abdomen of a Woman

JEADV Clinical Practice, EarlyView.
Ángel Fernández‐Camporro, Julián José Ahijado‐González, Eva Miranda‐Martínez   +2 more
wiley   +1 more source

Learning Trajectories for Constructing Mechanistic Explanations and the Role Played by Epistemic Knowledge

Science Education, EarlyView.
ABSTRACT Explaining scientific phenomena by unpacking their underlying mechanisms poses many challenges for high‐school students. One central challenge is synthesizing the different parts of a mechanism into a coherent whole and identifying what information is still missing, or whether further learning is required.
Ruth Molad, Michal Haskel‐Ittah
wiley   +1 more source

<i>Staphylococcus aureus</i> utilizes vimentin to internalize human keratinocytes. [PDF]

Front Cell Infect Microbiol
Jang K, Kim H, Choi D, Jang S, Chung DK.
europepmc   +1 more source

Spatially Profiling Trace Cytokine Signatures From Microscopically Derived Skin Samples to Probe Skin Disease Inflammation

Small Methods, EarlyView.
Inflammatory skin diseases are driven by immune dysregulation and cytokine imbalance. A challenge persists in profiling cytokines in microscopically derived biopsy skin samples due to low protein content. This study introduces a digital SERS immunoassay to simultaneously detect IL‐17A, IL‐22, IL‐23, and TNF at trace concentrations as low as 104 aM. The
Aditya Krishnakumar, Zhen Zhang, Courtney Vedelago, Timothy J. Liu, Yung‐Ching Kao, H. Peter Soyer, Mitchell S. Stark, Snehlata Kumari, Matt Trau, Alain Wuethrich   +9 more
wiley   +1 more source

Targeted Interference with USF2 Binding to the SERPINE1 Proximal Promoter E-Box in Dual Mutant p53^R282Q,H179Y Human Keratinocytes Inhibits Serum-/TGF-β1-Induced SERPINE1 Expression and Stimulates Epithelial Cell Proliferation. [PDF]

Biomedicines
Higgins SP, Czekay RP, Higgins CE, Higgins PJ.   +3 more
europepmc   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source