Results 231 to 240 of about 119,573 (312)

Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes. [PDF]

Sci Rep
Yun J, Kim JE.
europepmc   +1 more source

Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease

Pediatric Investigation, EarlyView.
Mei Kamidani, Ryo Tanaka, Hiroshi Oue, Risa Fukuda, Rena Hashimoto, Ichiro Takeuchi, Takako Yoshioka, Naoya Tonegawa, Akira Ishiguro, Katsuhiro Arai, Kazue Yoshida   +10 more
wiley   +1 more source

Sun‐Related Behaviours and Photoprotection Practices in an Australian Hospital Outpatient Setting: Findings From a Cross‐Sectional Survey

Australasian Journal of Dermatology, EarlyView.
ABSTRACT This cross‐sectional survey of 127 hospital outpatients assessed sun exposure behaviours and photoprotection practices. Photoprotection was inconsistent and often sub‐optimal, including among high‐risk individuals. Findings highlight the need for improved patient education and targeted counselling to promote comprehensive, guideline‐based ...
Jessica McClatchy, Vanessa Tran, Vanessa Morgan, Celestine Wong   +3 more
wiley   +1 more source

The Beneficial Effects of a N-(1-Carbamoyl-2-phenyl-ethyl) Butyramide on Human Keratinocytes. [PDF]

Pharmaceuticals (Basel)
Oglio F, Coppola S, Agizza A, Masino A, Luongo C, Di Santillo R, D'Auria L, Russo R, Neri I, Grumetto L, Carucci L, Caldaria E, Nocerino R, Di Lorenzo R, Calignano A, Laneri S, Paparo L, Berni Canani R.   +17 more
europepmc   +1 more source

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase–Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

Allergy, EarlyView.
Integrated methylome–transcriptome–microbiome analysis of AD skin identified thousands of DMRs. Rho GTPase signaling and actin–junctional programs emerged as central hubs integrating immune, epithelial, and microbial interactions in the pathogenesis of atopic dermatitis.
Tiina Skoog, Ying Yang, Peter Olah, Shintaro Katayama, Piia Karisola, Catherine Smith, Stephan Weidinger, Jonathan Barker, Antti Lauerma, Björn Andersson, Bernhard Homey, Nanna Fyhrquist, Juha Kere, Harri Alenius, MAARS Consortium, Francesca Levi‐Schaffer, Dario Greco, Stefanie Prast‐Nielsen, Vassili Soumelis, Sophia Tsoka, Jens M. Schröder, Frank O. Nestle, Philippe Hupé   +22 more
wiley   +1 more source

Benzo[a]pyrene and UV light co-exposure: differential effects on oxidative stress and genotoxicity in human keratinocytes and ex vivo skin. [PDF]

Arch Toxicol
Kersch C, Masutin V, Alsaleh R, Schmitz-Spanke S.   +3 more
europepmc   +1 more source

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

Clarifying the priming requirement and activator specificity for the NLRP3 inflammasome in human keratinocytes in vitro

Rozario P, Lim YS, Ding SSL, Firdaus MJ, Wearne S, Brandon WHS, Chua R, Robinson KS, Chu JTS, Meng L, Cai SSC, Tan STE, Wee SK, Lamers MM, Verma NK, Yun X, Yap EPH, Common JEA, Zhong F.   +18 more
europepmc   +1 more source

Protective Effects of Oleanolic Acid on Human Keratinocytes: A Defense Against Exogenous Damage. [PDF]

Pharmaceuticals (Basel)
Vasarri M, Bergonzi MC, Leri M, Castellacci R, Bucciantini M, De Marchi L, Degl'Innocenti D.   +6 more
europepmc   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source