Results 21 to 30 of about 400,125 (363)

Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia

open access: yesHaematologica, 2020
Human leukocyte antigen-G is a non-classical major histocompatibility complex class I antigen with potent immune-inhibitory function. Human leukocyte antigen-G benefit patients in allotransplantation and autoimmune diseases by interacting with its ...
Xin Li   +16 more
doaj   +1 more source

Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

open access: yesMedicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić   +5 more
doaj   +1 more source

Maternal and infant infections stimulate a rapid leukocyte response in breastmilk [PDF]

open access: yes, 2013
Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and
Filgueira, L   +6 more
core   +3 more sources

Human leukocyte antigen B27 [PDF]

open access: yesClinical Medicine, 2010
The year 1973 was quite an eventful one with key important milestones occurring in the political and scientific domains. It was the year when American troops finally withdrew from Vietnam, Pink Floyd released Dark side of the moon , and the UK joined the European Economic Community.
openaire   +3 more sources

The Frequency of HLA-A, HLA-B, and HLA-DRB1 Alleles in Patients with Acute Lymphoblastic Leukemia in the Turkish Population: A Case-Control Study

open access: yesTurkish Journal of Hematology, 2016
We studied the frequencies of human leukocyte antigen alleles (A, B, and DRB1) in 90 patients with acute lymphoblastic leukemia (ALL) and then compared them with 126 controls in this study. Although the frequencies of the A*03 allele, the DRB1*03 allele,
Türkan Patıroğlu, H. Haluk Akar
doaj   +1 more source

Innate immune basis for rift valley fever susceptibility in mouse models [PDF]

open access: yes, 2017
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre   +7 more
core   +2 more sources

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]

open access: yes, 2016
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D.   +8 more
core   +2 more sources

Animal lectins as cell adhesion molecules [PDF]

open access: yes, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

Accurate imputation of human leukocyte antigens with CookHLA [PDF]

open access: yesNature Communications, 2021
AbstractThe recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to previous methods.
Soumya Raychaudhuri   +11 more
openaire   +3 more sources

Improving Access to HLA-Matched Kidney Transplants for African American Patients

open access: yesFrontiers in Immunology, 2022
IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov   +8 more
doaj   +1 more source

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