Results 21 to 30 of about 348,506 (362)
Human leukocyte antigen B27 [PDF]
Clinical Medicine, 2010 The year 1973 was quite an eventful one with key important milestones occurring in the political and scientific domains. It was the year when American troops finally withdrew from Vietnam, Pink Floyd released Dark side of the moon , and the UK joined the European Economic Community.
openaire +3 more sources
The viral transcription group determines the HLA class I cellular immune response against human respiratory syncytial virus [PDF]
, 2015 The cytotoxic T-lymphocyte-mediated killing of virus-infected cells requires previous recognition of short viral antigenic peptides bound to human leukocyte antigen class I molecules that are exposed on the surface of infected cells.
Akram +62 more
core +2 more sources
Turkish Journal of Hematology, 2016 We studied the frequencies of human leukocyte antigen alleles (A, B, and DRB1) in 90 patients with acute lymphoblastic leukemia (ALL) and then compared them with 126 controls in this study. Although the frequencies of the A*03 allele, the DRB1*03 allele,
Türkan Patıroğlu, H. Haluk Akar
doaj +1 more source
Accurate imputation of human leukocyte antigens with CookHLA [PDF]
Nature Communications, 2021 AbstractThe recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to previous methods.
Soumya Raychaudhuri +11 more
openaire +3 more sources
Improving Access to HLA-Matched Kidney Transplants for African American Patients
Frontiers in Immunology, 2022 IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov +8 more
doaj +1 more source
Genes predisposing to type 1 diabetes mellitus and pathophysiology: a narrative review [PDF]
arXiv, 2021 The possibility of targeting the causal genes along with the mechanisms of pathogenically complex diseases has led to numerous studies on the genetic etiology of some diseases. In particular, studies have added more genes to the list of type 1 diabetes mellitus (T1DM) suspect genes, necessitating an update for the interest of all stakeholders ...
arxiv
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. [PDF]
, 2015 Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific antibodies (DSA) binding donor Class I and II HLA (HLA-I and HLA-II) expressed on endothelial cells.
Fishbein, MC +7 more
core +1 more source
Studies on the Contact Sensitization of Man with Simple Chemicals [PDF]
, 1975 Dinitrochlorobenzene (DNCB) coupled to peripheral blood erythrocytes or leukocytes forms a particulate complex, DNCB-antigen. The addition of DNCB-antigen induced blastogenesis and DNA synthesis in leukocyte cultures from DNCB-sensitized human subjects ...
Levis, William R. +2 more
core +1 more source
Haematologica, 2012 Background Polymorphic differences between donor and recipient human leukocyte antigen class I molecules can result in graft-versus-host disease due to distinct peptide presentation. As part of the peptide-loading complex, tapasin plays an important role
Soumya Badrinath +6 more
doaj +1 more source
Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core +1 more source