Results 71 to 80 of about 23,100 (164)

Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes. [PDF]

Toxicol Rep, 2022
Abass K, Reponen P, Alsanie WF, Rautio A, Pelkonen O.   +4 more
europepmc   +1 more source

Identification and cross-species comparison of in vitro phase I brevetoxin (BTX-2) metabolites in northern Gulf of Mexico fish and human liver microsomes by UHPLC-HRMS(/MS). [PDF]

Toxicon X, 2023
Gwinn JK, Robertson A, Ivanova L, Fæste CK, Kryuchkov F, Uhlig S.   +5 more
europepmc   +1 more source

Targeted Metabolomics of Organophosphate Pesticides and Chemical Warfare Nerve Agent Simulants Using High- and Low-Dose Exposure in Human Liver Microsomes. [PDF]

Metabolites, 2023
Agarwal G, Tichenor H, Roo S, Lane TR, Ekins S, McElroy CA.   +5 more
europepmc   +1 more source

Characterization of 3-Hydroxyeticyclidine (3-HO-PCE) Metabolism in Human Liver Microsomes and Biological Samples Using High-Resolution Mass Spectrometry. [PDF]

Metabolites, 2023
Larabi IA, Joseph D, Lesueur C, Alvarez JC.   +3 more
europepmc   +1 more source

Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes. [PDF]

Molecules, 2023
Attwa MW, AlRabiah H, Kadi AA.
europepmc   +1 more source

Herb-drug interaction of Astragali Radix based on in vitro incubation and pharmacokinetic assessment

BMC Complementary Medicine and Therapies
Background Astragali Radix (AR) is extensively utilized in Asia for its various pharmacological effects. With the widespread use of AR, the risk of herb-drug interactions (HDIs) mediated by cytochrome P450 (P450) enzymes has become a serious concern ...
Tianwang Wang, Tingting Zhang, Xiaofei Chen, Chonggang Huang, Pengfei Tu, Kai Wang, Feng Qiu   +6 more
doaj   +1 more source

When Cofactors Aren't X Factors: Functional Groups That Are Labile in Human Liver Microsomes in the Absence of NADPH. [PDF]

ACS Med Chem Lett, 2022
Landry ML, Trager R, Broccatelli F, Crawford JJ.   +3 more
europepmc   +1 more source

Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes. [PDF]

Metabolites, 2022
Crosby SV, Ahmed IY, Osborn LR, Wang Z, Schleiff MA, Fantegrossi WE, Nagar S, Prather PL, Boysen G, Miller GP.   +9 more
europepmc   +1 more source

Metabolism of Diterpenoids Derived from the Bark of Cinnamomum cassia in Human Liver Microsomes. [PDF]

Pharmaceutics, 2021
Choi SM, Pham VC, Lee S, Kim JA.
europepmc   +1 more source

A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes. [PDF]

RSC Adv, 2022
Attwa MW, Abdelhameed AS, Alsaif NA, Kadi AA, AlRabiah H.   +4 more
europepmc   +1 more source