Results 181 to 190 of about 1,389,274 (311)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Molecular Pharmacology of Human Metabolism Diseases. [PDF]

Int J Mol Sci
Bułdak Ł.
europepmc   +1 more source

Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation. [PDF]

ACS Chem Biol, 2022
Schachner LF, Soye BD, Ro S, Kenney GE, Ives AN, Su T, Goo YA, Jewett MC, Rosenzweig AC, Kelleher NL.   +9 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Characterization Of In Vitro Metabolism of Brucine Using Human Liver Microsomes

, 2010
Background. Brucine, one of the bitter alkaloids isolated from Chinese folk medicine Strychnos nux-vomica L. (Loganiaceae), is known as an effective analgesic and anti- inflammatory agent for relieving arthritic and traumatic pain.
房中则, 葛广波, Ling Yang, 杨凌, 毛玉玺   +4 more
core  

Cold exposure and human metabolism: A heterogeneous response across tissues and organs. [PDF]

Temperature (Austin)
Tetzlaff EJ, Hancock C, Waddell L, Gagnon SS, Mäkelä KA, Karhu T, Peltonen JE, Herzig KH, Gagnon DD.   +8 more
europepmc   +1 more source

Design of highly sensitive biosensors using hollow-core microstructured fibers for plasma sensing in aids with human metabolism. [PDF]

Opt Quantum Electron, 2023
Alam MK, Vadivel K, Natesan A, Sghaireen MG, Ganji KK, Srivastava KC, Nashwan S, Khader Y.   +7 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Meal Timing and Macronutrient Composition Modulate Human Metabolism and Reward-Related Drive to Eat. [PDF]

Nutrients, 2022
Chamorro R, Kannenberg S, Wilms B, Kleinerüschkamp C, Meyhöfer S, Park SQ, Lehnert H, Oster H, Meyhöfer SM.   +8 more
europepmc   +1 more source