Results 191 to 200 of about 1,389,274 (311)

Human Fecal Metabolism of Soyasaponin I

open access: yes, 2004
The metabolism of soyasaponin I (3-O-[alpha-L-rhamnopyranosyl-beta-D-galactopyranosyl-beta-D-glucuronopyranosyl]olean-12-ene-3beta,22beta,24-triol) by human fecal microorganisms was investigated.
Zheng, Yan   +4 more
core  

Insights into the human metabolism and in silico receptor activity of gidazepam and desalkylgidazepam. [PDF]

open access: yesArch Toxicol
Gameli PS   +7 more
europepmc   +1 more source

A dynamic multi-tissue model to study human metabolism. [PDF]

open access: yesNPJ Syst Biol Appl, 2021
Martins Conde P   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

A genetic map of human metabolism across the allele frequency spectrum. [PDF]

open access: yesNat Genet
Zoodsma M   +10 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

C11orf54 catalyzes L-xylulose formation in human metabolism. [PDF]

open access: yesProc Natl Acad Sci U S A
Malatesta M   +7 more
europepmc   +1 more source

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