Results 11 to 20 of about 2,261,504 (355)
Frontiers in Chemistry, 2020 Trenbolone is a synthetic anabolic-androgenic steroid, which has been misused for performance enhancement in sports. The detection of trenbolone doping in routine sports drug testing programs is complex as methods utilizing gas chromatography/mass ...
Marlen Putz, Thomas Piper, Mario Thevis
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A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. [PDF]
, 2020 Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly ...
Balskus, Emily P +8 more
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Angewandte Chemie International Edition, 2022 AbstractOdorants are relatively small molecules which are easily taken up and distributed in the human body. Despite their relevance in everyday life, however, only a limited amount of evidence about their metabolism, pathways, and bioactivities in the human body exists.
Nicole Kornbausch +4 more
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Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]
, 2015 BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R. +13 more
core +5 more sources
iScience, 2023 Summary: Skin plays central roles in systemic physiology, and it undergoes significant functional changes during aging. Members of the peroxisome proliferator-activated receptor-gamma coactivator (PGC-1) family (PGC-1s) are key regulators of the biology ...
Simon-Pierre Gravel +12 more
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MiR-203 is an anti-obese microRNA by targeting apical sodium-dependent bile acid transporter
iScience, 2022 Summary: Obesity is characterized by excessive fat deposition within the body. Bile acids (BA) are important regulators for controlling the absorption of lipid.
Xin Liu +17 more
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Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease
Frontiers in Endocrinology, 2019 Endocrine disrupting chemicals (EDCs), a heterogeneous group of exogenous chemicals that can interfere with any aspect of endogenous hormones, represent an emerging global threat for human metabolism.
Olga Papalou +3 more
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Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome
Molecular Systems Biology, 2020 Comprehensive molecular‐level models of human metabolism have been generated on a cellular level. However, models of whole‐body metabolism have not been established as they require new methodological approaches to integrate molecular and physiological ...
Ines Thiele +6 more
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Morphine Metabolism in Human Skin Microsomes [PDF]
, 2012 For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S. +2 more
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BBA Clinical, 2016 In the human body, glycogen is a branched polymer of glucose stored mainly in the liver and the skeletal muscle that supplies glucose to the blood stream during fasting periods and to the muscle cells during muscle contraction. Glycogen has been identified in other tissues such as brain, heart, kidney, adipose tissue, and erythrocytes, but glycogen ...
Adeva-Andany, María M. +4 more
openaire +2 more sources