Results 21 to 30 of about 1,389,274 (311)

MiR-203 is an anti-obese microRNA by targeting apical sodium-dependent bile acid transporter

iScience, 2022
Summary: Obesity is characterized by excessive fat deposition within the body. Bile acids (BA) are important regulators for controlling the absorption of lipid.
Xin Liu, Feiran Cheng, Xue Bai, Tong Zhao, Limin Zhao, Lei Wang, Mingqi Li, Xianxian Wu, Xiaohui Chen, Pingping Tang, Mengxue Wang, Lintong Jiang, Chaoqi Yan, Fenghua Pei, Xu Gao, Ning Ma, Baofeng Yang, Yong Zhang   +17 more
doaj   +1 more source

Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease

Frontiers in Endocrinology, 2019
Endocrine disrupting chemicals (EDCs), a heterogeneous group of exogenous chemicals that can interfere with any aspect of endogenous hormones, represent an emerging global threat for human metabolism.
Olga Papalou, Eleni A. Kandaraki, George Papadakis, Evanthia Diamanti-Kandarakis   +3 more
doaj   +1 more source

Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome

Molecular Systems Biology, 2020
Comprehensive molecular‐level models of human metabolism have been generated on a cellular level. However, models of whole‐body metabolism have not been established as they require new methodological approaches to integrate molecular and physiological ...
Ines Thiele, Swagatika Sahoo, Almut Heinken, Johannes Hertel, Laurent Heirendt, Maike K Aurich, Ronan MT Fleming   +6 more
doaj   +1 more source

Health Effects and Mechanisms of Inulin Action in Human Metabolism. [PDF]

Nutrients
Inulin is a plant polysaccharide which, due to its chemical structure, is not digestible by human gut enzymes but by some bacteria of the human microbiota, acting as a prebiotic.
Alonso-Allende J, Milagro FI, Aranaz P.
europepmc   +2 more sources

Odorant Metabolism in Humans

Angewandte Chemie International Edition, 2022
AbstractOdorants are relatively small molecules which are easily taken up and distributed in the human body. Despite their relevance in everyday life, however, only a limited amount of evidence about their metabolism, pathways, and bioactivities in the human body exists.
Nicole Kornbausch, Marcel W. Debong, Andrea Buettner, Jean‐Marie Heydel, Helene M. Loos   +4 more
openaire   +3 more sources

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease

Frontiers in Physiology, 2014
Membrane transporters enable efficient cellular metabolism, aid in nutrient sensing, and have been associated with various diseases, such as obesity and cancer.
Swagatika eSahoo, Swagatika eSahoo, Maike Kathrin Aurich, Jon Johannes Jonsson, Ines eThiele, Ines eThiele   +5 more
doaj   +1 more source

Effects of a combined protein and antioxidant supplement on recovery of muscle function and soreness following eccentric exercise

Journal of the International Society of Sports Nutrition, 2017
Background An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS).
Stephen J. Ives, Samuel Bloom, Alexs Matias, Noelle Morrow, Natalya Martins, Yookee Roh, Daniel Ebenstein, Gabriel O’Brien, Daniela Escudero, Kevin Brito, Leah Glickman, Scott Connelly, Paul J. Arciero   +12 more
doaj   +1 more source

Cystatin C is associated with adverse COVID-19 outcomes in diverse populations

iScience, 2022
Summary: COVID-19 has highly variable clinical courses. The search for prognostic host factors for COVID-19 outcome is a priority. We performed logistic regression for ICU admission against a polygenic score (PGS) for Cystatin C (CyC) production in ...
Sam O. Kleeman, Mattia Cordioli, Paul R.H. J. Timmers, Atlas Khan, Pinkus Tober-Lau, Florian Kurth, Vadim Demichev, Hannah V. Meyer, James F. Wilson, Markus Ralser, Krzysztof Kiryluk, Andrea Ganna, Kenneth Baillie, Tobias Janowitz   +13 more
doaj   +1 more source

The role of the endoplasmic reticulum in the metabolism of "xenobiotica" [PDF]

, 2013
Short-chain dehydrogenase/reductase (SDR) enzymes play a key role in the metabolism of steroids, fatty acids, prostaglandins and xenobiotic chemicals.
Meyer, Arne
core   +1 more source