Results 11 to 20 of about 1,287,033 (265)

SULFUR CONTAINING MINERAL WATER AS A DIETARY FACTOR CHALLENGING THE PHASE II DETOXIFICATION ENZYMES IN HUMAN INTESTINAL CELLS [PDF]

Journal of IMAB, 2022
Introduction: According to the scientific literature, sulfur contained in various foods and medicines is almost completely absorbed in the gastrointestinal tract.
Todorka Sokrateva, Oskan Tasinov, Stefka Stoeva, Diana Ivanova, Neshe Nazifova-Tasinova, Milka Nashar   +5 more
doaj   +1 more source

An atlas of human metabolism. [PDF]

Sci Signal, 2020
An open-source, genome-scale human metabolic model and a web portal to explore the model are generated.
Robinson JL, Kocabaş P, Wang H, Cholley PE, Cook D, Nilsson A, Anton M, Ferreira R, Domenzain I, Billa V, Limeta A, Hedin A, Gustafsson J, Kerkhoven EJ, Svensson LT, Palsson BO, Mardinoglu A, Hansson L, Uhlén M, Nielsen J.   +19 more
europepmc   +9 more sources

Link between glucose metabolism and epithelial-to-mesenchymal transition drives triple-negative breast cancer migratory heterogeneity

iScience, 2022
Summary: Intracellular and environmental cues result in heterogeneous cancer cell populations with different metabolic and migratory behaviors. Although glucose metabolism and epithelial-to-mesenchymal transition have previously been linked, we aim to ...
Samantha C. Schwager, Jenna A. Mosier, Reethi S. Padmanabhan, Addison White, Qinzhe Xing, Lauren A. Hapach, Paul V. Taufalele, Ismael Ortiz, Cynthia A. Reinhart-King   +8 more
doaj   +1 more source

Human metabolic atlas: an online resource for human metabolism [PDF]

Database, 2015
Human tissue-specific genome-scale metabolic models (GEMs) provide comprehensive understanding of human metabolism, which is of great value to the biomedical research community. To make this kind of data easily accessible to the public, we have designed and deployed the human metabolic atlas (HMA) website (http://www.metabolicatlas.org).
Natapol Pornputtapong, Intawat Nookaew, Jens Nielsen   +2 more
openaire   +2 more sources

Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes

iScience, 2021
Summary: Inflammaging is associated with an increased risk of chronic disease. Monocytes are the principal immune cells for the production of inflammatory cytokines and contribute to inflammaging in the elderly.
Ming Wang, Yan Yan, Zhengguo Zhang, Xiaohan Yao, Xixi Duan, Ziming Jiang, Junfeng An, Peiguo Zheng, Yijie Han, Hao Wu, Zhaoqing Wang, Rainer Glauben, Zhihai Qin   +12 more
doaj   +1 more source

Manganese metabolism in humans [PDF]

Frontiers in Bioscience, 2018
Manganese (Mn) is an essential nutrient for intracellular activities; it functions as a cofactor for a variety of enzymes, including arginase, glutamine synthetase (GS), pyruvate carboxylase and Mn superoxide dismutase (Mn-SOD). Through these metalloproteins, Mn plays critically important roles in development, digestion, reproduction, antioxidant ...
Chen, Pan, Bornhorst, Julia (Dr.), Aschner, Michael (Prof.)   +2 more
openaire   +2 more sources

Intermittent fasting two days versus one day per week, matched for total energy intake and expenditure, increases weight loss in overweight/obese men and women

Nutrition Journal, 2022
Background Intermittent fasting (IF), consisting of either a one-day (IF1) or two consecutive days (IF2) per week, is commonly used for optimal body weight loss.
Paul J. Arciero, Karen M. Arciero, Michelle Poe, Alex E. Mohr, Stephen J. Ives, Autumn Arciero, Molly Boyce, Jin Zhang, Melissa Haas, Emma Valdez, Delaney Corbet, Kaitlyn Judd, Annika Smith, Olivia Furlong, Marley Wahler, Eric Gumpricht   +15 more
doaj   +1 more source

Glycogen metabolism in humans

BBA Clinical, 2016
In the human body, glycogen is a branched polymer of glucose stored mainly in the liver and the skeletal muscle that supplies glucose to the blood stream during fasting periods and to the muscle cells during muscle contraction. Glycogen has been identified in other tissues such as brain, heart, kidney, adipose tissue, and erythrocytes, but glycogen ...
Adeva-Andany, María M., González-Lucán, Manuel, Donapetry-García, Cristóbal, Fernández-Fernández, Carlos, Ameneiros-Rodríguez, Eva   +4 more
openaire   +2 more sources

Metabolic Imaging in Humans [PDF]

Topics in Magnetic Resonance Imaging, 2016
Metabolic imaging enhances understanding of disease metabolisms and holds great potential as a measurement tool for evaluating disease prognosis and treatment effectiveness. Advancement of techniques, such as magnetic resonance spectroscopy, positron emission tomography, and mass spectrometry, allows for improved accuracy for quantification of ...
Taylor L, Fuss, Leo L, Cheng
openaire   +2 more sources

PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation

iScience, 2023
Summary: Skin plays central roles in systemic physiology, and it undergoes significant functional changes during aging. Members of the peroxisome proliferator-activated receptor-gamma coactivator (PGC-1) family (PGC-1s) are key regulators of the biology ...
Simon-Pierre Gravel, Youcef Ben Khalifa, Shawn McGuirk, Catherine St-Louis, Karl M. Laurin, Émilie Lavallée, Damien Benas, Stéphanie Desbouis, Frédéric Amaral, Damien D’Amours, Lionel Breton, Sibylle Jäger, Julie St-Pierre   +12 more
doaj   +1 more source