Results 31 to 40 of about 1,287,033 (265)
Frontiers in Physiology, 2022 The ideal exercise time of day (ETOD) remains elusive regarding simultaneous effects on health and performance outcomes, especially in women.Purpose: Given known sex differences in response to exercise training, this study quantified health and ...
Paul J. Arciero +22 more
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On the Metabolism of Exogenous Ketones in Humans [PDF]
Frontiers in Physiology, 2017 Background and aims: Currently there is considerable interest in ketone metabolism owing to recently reported benefits of ketosis for human health. Traditionally, ketosis has been achieved by following a high-fat, low-carbohydrate "ketogenic" diet, but adherence to such diets can be difficult. An alternative way to increase blood D-β-hydroxybutyrate (D-
Brianna J. Stubbs +10 more
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iScienceSummary: Insulin plays a crucial role in regulating the metabolism of blood glucose, amino acids (aa), and lipids in humans. However, the mechanisms by which insulin selectively regulates these metabolites are not fully understood.
Suguru Fujita +3 more
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Frontiers in Physiology, 2014 Membrane transporters enable efficient cellular metabolism, aid in nutrient sensing, and have been associated with various diseases, such as obesity and cancer.
Swagatika eSahoo +5 more
doaj +1 more source
Teicoplanin metabolism in humans
Antimicrobial Agents and Chemotherapy, 1992 Teicoplanin, a lipoglycopeptide antibiotic, consists of five major components (A2-1 through A2-5), one hydrolysis component (A3-1), and four minor components (RS-1 through RS-4). All the major components contain an N-acyl-beta-D-glucosamine, but they differ in the lengths and branchings of their acyl-aliphatic chains. Previous studies with radiolabeled
A, Bernareggi +7 more
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Genetics of human metabolism: an update [PDF]
Human Molecular Genetics, 2015 Genome-wide association studies with metabolomics (mGWAS) identify genetically influenced metabotypes (GIMs), their ensemble defining the heritable part of every human's metabolic individuality. Knowledge of genetic variation in metabolism has many applications of biomedical and pharmaceutical interests, including the functional understanding of ...
Gabi Kastenmüller +3 more
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Androgen Metabolism in Human Skin [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1971 ABSTRACT Androgen metabolism has been studied in fetal and adult skin with definitive identification of radiometabolites and the use of a computerized technique for their quantitative determination. After infusion of testosterone-4-14C to previable fetuses, from the 12th to 22nd week of gestation, there was a higher proportion of untransformed ...
CARLO FLAMIGNI +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source