Results 51 to 60 of about 1,389,274 (311)

The environment within: how gut microbiota may influence metabolism and body composition

, 2010
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and staggering prevalence of obesity might not only be explained by nutritional habits or the reduction of ...
Vos, W.M., de, A. Vrieze, Hoekstra, J. B. L., E. G. Zoetendal, Zoetendal, E.G., F. Holleman, Vrieze, A., W. M. de Vos, J. B. L. Hoekstra, M. Nieuwdorp, Holleman, F., Zoetendal, E. G., Hoekstra, J.B., de Vos, W. M., de Vos, W.M., Nieuwdorp, M.   +15 more
core   +1 more source

Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. [PDF]

, 2004
BACKGROUND: Some animal studies have suggested that conjugated linoleic acid (CLA) supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors ...
Mullen, Anne, Anne Mullen, John J Nolan, Moloney, F, Yeow, Toh-Peng, Toh-Peng Yeow, Helen M Roche, Yeow, TP, Roche, HM, Fiona Moloney, Mullen, A, Nolen, JJ, Moloney, Fiona, Nolan, John J, Roche, Helen M   +14 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An Update of the Promise of Glycine Supplementation for Enhancing Physical Performance and Recovery

Sports
Glycine, the simple amino acid, is a key component of muscle metabolism with proven cytoprotective effects and hypothetical benefits as a therapeutic nutrient.
Arnulfo Ramos-Jiménez, Rosa Patricia Hernández-Torres, David Alfredo Hernández-Ontiveros, Melinna Ortiz-Ortiz, Reymond Josué López-Fregoso, José Miguel Martínez-Sanz, Genaro Rodríguez-Uribe, Marco Antonio Hernández-Lepe   +7 more
doaj   +1 more source

Resistant Starch Combined with Whey Protein Increases Postprandial Metabolism and Lowers Glucose and Insulin Responses in Healthy Adult Men

Foods, 2021
Resistant starch (RS) and/or protein consumption favorably influence energy metabolism, substrate utilization, and weight management. The current study administered four different versions of a pancake breakfast containing waxy maize or RS with and ...
Alex E. Mohr, Olivia Minicucci, Dale Long, Vincent J. Miller, Allison Keller, Caitlin Sheridan, Gabriel O’brien, Emery Ward, Brad Schuler, Scott Connelly, Jens J. Holst, Arne Astrup, Feng He, Christopher L. Gentile, Paul J. Arciero   +14 more
doaj   +1 more source

Metabolism of glucose by human embryos [PDF]

International Journal of Gynecology & Obstetrics, 1987
Summary. Glucose turnover, as measured by CO2 production, lactate accumulation and carbon incorporation from [U-14C]glucose as sole energy substrate, was low on the 2nd day of culture of human embryos resulting from in-vitro fertilization but above that of unfertilized oocytes.
R G, Wales, D G, Whittingham, K, Hardy, I L, Craft   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

GLP-1 receptor agonists and acute diabetes complications in adults with type 1 diabetes

iScience
Summary: GLP-1 receptor agonists (GLP-1 RAs) are increasingly used for weight management in patients with obesity, yet their safety in those with comorbid type 1 diabetes (T1D) remains uncertain due to concerns about diabetic ketoacidosis (DKA).
Hao Dai, Yao An Lee, Rotana M. Radwan, Amy J. Sheer, Tamara S. Hannon, Matthew R. Hayes, Ramon C. Sun, Jiang Bian, Jingchuan Guo   +8 more
doaj   +1 more source

Liver glucose metabolism in humans [PDF]

Bioscience Reports, 2016
Information about normal hepatic glucose metabolism may help to understand pathogenic mechanisms underlying obesity and diabetes mellitus. In addition, liver glucose metabolism is involved in glycosylation reactions and connected with fatty acid metabolism.
Adeva-Andany, María M., Pérez-Felpete, Noemi, Fernández-Fernández, Carlos, Donapetry-García, Cristóbal, Pazos-García, Cristina   +4 more
openaire   +2 more sources