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A framework for human microbiome research. [PDF]
A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a ...
Human Microbiome Project Consortium
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In 2011, at the Society for Integrative Oncology's international meeting in Cleveland, Ohio, Francis Collins, PhD, head of the National Institutes of Health, shocked the audience when he asserted that although his work in the human genome was exciting, he was more impressed by the potential represented by the National Institutes of Health's investment ...
Gregory A. Plotnikoff, David R. Riley
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The human microbiome (glossary in Appendix 1, available at [www.cmaj.ca/lookup/suppl/doi:10.1503/cmaj.141072/-/DC1][1]) comprises hundreds of previously known and newly discovered microbial species living in distinct communities adapted to specific anatomic sites.[1][2] In healthy adults ...
Bryan Coburn, David S. Guttman
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The sequencing of the human genome has driven the study of human biology in a significant way and enabled the genome-wide study to elucidate the molecular basis of complex human diseases. Recently, the role of microbiota on human physiology and health has received much attention.
Paramasamy Gunasekaran +1 more
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The human microbiome refers to the complex microbial ecosystems that colonize different niches in our bodies and significantly impact homeostasis and overall health. The most studied is certainly the gut microbiome, but knowledge is also increasing on the oral, cutaneous, vaginal communities, etc.
Giulio Maria Pasinetti +3 more
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The microbiome as a human organ [PDF]
The human organism is a complex structure composed of cells belonging to all three domains of life on Earth, Eukarya, Bacteria and Archaea, as well as their viruses. Bacterial cells of more than a thousand taxonomic units are condensed in a particular functional collective domain, the intestinal microbiome.
Baquero, Fernando, Nombela, César
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The microbiome and human cancer
BACKGROUND Historical accounts linking cancer and microbes date as early as four millennia ago. After establishment of the germ theory of infectious diseases, clinical research of microbial influences on cancer began in 1868, when William Busch reported spontaneous tumor regressions in patients with
Sepich-Poore, Gregory +5 more
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A microbiome is defined as the aggregate of all microbiota that reside in human digestive system and other tissues. This microbiota includes viruses, bacteria, fungi that live in various human organs and tissues like stomach, guts, oesophagus, mouth cavity, urinary tract, vagina, lungs, and skin.
Mohammad Menati Rashno +3 more
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Context and the human microbiome [PDF]
Human microbiome reference datasets provide epidemiological context for researchers, enabling them to uncover new insights into their own data through meta-analyses. In addition, large and comprehensive reference sets offer a means to develop or test hypotheses and can pave the way for addressing practical study design considerations such as sample ...
McDonald, Daniel +2 more
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The Effect of Antibiotics on the Infant Gut Fungal Microbiota
Antibiotics are commonly used drugs in infants, causing disruptions in the developing gut microbiota with possible detrimental long-term effects such as chronic inflammatory diseases.
Rebecka Ventin-Holmberg +7 more
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