Results 61 to 70 of about 296,797 (348)

The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome. [PDF]

, 2016
Many human skin diseases, such as seborrheic dermatitis, potentially occur due to the over-growth of fungi. It remains a challenge to develop fungicides with a lower risk of generating resistant fungi and non-specifically killing commensal microbes.
Barshop, Bruce A, Chen, Wan-Tzu, Gallo, Richard L, Gangoiti, Jon A, Hsieh, Ming-Fa, Huang, Chun-Jen, Huang, Chun-Ming, Huang, Stephen, Hyun, Choi, Kao, Ming-Shan, Lee, Woan-Ruah, Lin, Wan-Zhen, Marito, Shinta, Ran, Yuping, Sanford, James A, Wang, Yanhan   +15 more
core   +1 more source

The Human Microbiome and Cancer [PDF]

Cancer Prevention Research, 2017
Abstract Recent scientific advances have significantly contributed to our understanding of the complex connection between the microbiome and cancer. Our bodies are continuously exposed to microbial cells, both resident and transient, as well as their byproducts, including toxic metabolites. Circulation of toxic metabolites may contribute
Venter Jc, Karen E. Nelson, Oldfield Lm, Amalio Telenti, Sanjay Vashee, Seesandra V. Rajagopala, Yo Suzuki   +6 more
openaire   +2 more sources

Enterotypes of the human gut microbiome [PDF]

Nature, 2011
Our knowledge of species and functional composition of the human gut microbiome is rapidly increasing, but it is still based on very few cohorts and little is known about variation across the world. By combining 22 newly sequenced faecal metagenomes of individuals from four countries with previously published data sets, here we identify three robust ...
Arumugam, Manimozhiyan, Raes, Jeroen, Pelletier, Eric, Le Paslier, Denis, Yamada, Takuji, Mende, Daniel R., Fernandes, Gabriel R., Tap, Julien, Bruls, Thomas, Batto, Jean-Michel, Bertalan, Marcelo, Borruel, Natalia, Casellas, Francesc, Fernandez, Leyden, Gautier, Laurent, Hansen, Torben, Hattori, Masahira, Hayashi, Tetsuya, Kleerebezem, Michiel, Kurokawa, Ken, Leclerc, Marion, Levenez, Florence, Manichanh, Chaysavanh, Nielsen, H. Bjørn, Nielsen, Trine, Pons, Nicolas, Poulain, Julie, Qin, Junjie, Sicheritz-Ponten, Thomas, Tims, Sebastian, Torrents, David, Ugarte, Edgardo, Zoetendal, Erwin G., Wang, Jun, Guarner, Francisco, Pedersen, Oluf, de Vos, Willem M., Brunak, Søren, Doré, Joel, Antolín, María, Artiguenave, François, Blottiere, Hervé M., Almeida, Mathieu, Brechot, Christian, Cara, Carlos, Chervaux, Christian, Cultrone, Antonella, Delorme, Christine, Denariaz, Gérard, Dervyn, Rozenn, Foerstner, Konrad U., Friss, Carsten, van de Guchte, Maarten, Guedon, Eric, Haimet, Florence, Huber, Wolfgang, van Hylckama-Vlieg, Johan, Jamet, Alexandre, Juste, Catherine, Kaci, Ghalia, Knol, Jan, Lakhdari, Omar, Layec, Severine, Le Roux, Karine, Maguin, Emmanuelle, Mérieux, Alexandre, Melo Minardi, Raquel, M'rini, Christine, Muller, Jean, Oozeer, Raish, Parkhill, Julian, Renault, Pierre, Rescigno, Maria, Sanchez, Nicolas, Sunagawa, Shinichi, Torrejon, Antonio, Turner, Keith, Vandemeulebrouck, Gaetana, Varela, Encarna, Winogradsky, Yohanan, Zeller, Georg, Weissenbach, Jean, Ehrlich, S. Dusko, Bork, Peer   +83 more
openaire   +7 more sources

Host genetic variation impacts microbiome composition across human body sites [PDF]

, 2015
Background: The composition of bacteria in and on the human body varies widely across human individuals, and has been associated with multiple health conditions.
Alon Keinan, Andrew G. Clark, Dirk Gevers, Jordana T. Bell, Julia K. Goodrich, Katherine Huang, Qi Sun, Ran Blekhman, Robert Bukowski, Ruth E. Ley, Timothy D. Spector   +10 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Stimulatory Effects of Extracellular Vesicles Derived from Leuconostoc holzapfelii That Exists in Human Scalp on Hair Growth in Human Follicle Dermal Papilla Cells

Current Issues in Molecular Biology, 2022
Human hair follicle dermal papilla cells (HFDPCs) located in hair follicles (HFs) play a pivotal role in hair follicle morphogenesis, hair cycling, and hair growth.
Yeo Cho Yoon, Beom Hee Ahn, Jin Woo Min, Kyung Real Lee, Sang Hoon Park, Hee Cheol Kang   +5 more
doaj   +1 more source

Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]

, 2019
The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R, Durbin-Johnson, Blythe P, Elizaldi, Sonny R, Iyer, Smita S, Kozlowski, Pamela A, Raeman, Reben, Rolston, Matthew, Settles, Matthew, Verma, Anil, Walter, Korey A   +9 more
core   +1 more source

Bioarchaeology of the Human Microbiome [PDF]

Bioarchaeology International, 2017
From prehistory to the present, microbes have played a significant role in the development of human society and culture—from providing essential nutrients and protection through the microbiome, to shaping populations through infectious disease, to producing fermented foods such as cheese, bread, and beer.
Velsko, I., Warinner, C.
openaire   +3 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information [PDF]

, 2010
The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information.
Baranova, Oxana V., Chen, Tsute, Dewhirst, Floyd E., Izard, Jacques, Lakshmanan, Abirami, Yu, Wen-Han   +5 more
core   +1 more source