Results 241 to 250 of about 515,553 (312)

Concentration and Intakes of Macronutrients from Human Milk Do Not Differ by Infant Sex in Australian and Danish Cohorts. [PDF]

Nutrients
Honoré KD, Lai CT, Michaelsen KF, Gridneva Z, Zachariassen G, Geddes DT.   +5 more
europepmc   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Associations of known and newly identified human milk oligosaccharides with infections in early childhood: the Ulm SPATZ health study. [PDF]

Front Immunol
Siziba LP, Peng Z, Mank M, Stahl B, Gonsalves J, Wernecke D, Rothenbacher D, Genuneit J.   +7 more
europepmc   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Analysis of the economic benefits and feasibility of the same-city delivery model for donor human milk (SCDM-DHM). [PDF]

Int Breastfeed J
Yin D, Yi Y, Huang K, Chen Y, Zheng H, Zhou P, Zhang L, Yu Z, Zhang Q, Cai J, Xing R, Zhou K.   +11 more
europepmc   +1 more source

Composition of the human milk microbiome in the GUSTO cohort is shaped by intrapartum antibiotic prophylaxis and breastfeeding exclusivity

Lisa F. Stinson, Wei Wei Pang, Alethea Rea, Doris Fok, Mei Chien Chua, Kok Hian Tan, Fabian Yap, Keith M. Godfrey, Lynette Pei‐Chi Shek, Johan G. Eriksson, Yap Seng Chong, Shiao-Yng Chan, Mary E. Wlodek, Donna T. Geddes   +13 more
openalex   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Maternal obesity alters human milk oligosaccharides content and correlates with early acquisition of late colonizers in the neonatal gut microbiome. [PDF]

Gut Microbes
Corona-Cervantes K, Urrutia-Baca VH, Gámez-Valdez JS, Jiménez-López B, Rodríguez-Gutierrez NA, Chávez-Caraza K, Espiricueta-Candelaria F, Villalobos UAS, Ramos-Parra PA, Uribe JAG, Brunck M, Chuck-Hernández C, Licona-Cassani C.   +12 more
europepmc   +1 more source

The Association Between Maternal Diet and the Human Milk Microbiome: A Review of Evidence and Methodological Challenges. [PDF]

Microorganisms
Sindi AS.
europepmc   +1 more source

Cytokines and appetite-regulating hormones in human milk and associations with infant growth across four sites in a longitudinal cohort: The Mothers, Infants and Lactation Quality Study

Sophie Hilario Christensen, Jack Windsor Lewis, Hanne Frøkiær, Peter Riber Johnsen, Janet M Peerson, Xiuping Tan, Setareh Shahab‐Ferdows, Daniela Hampel, M Munirul Islam, Gilberto Kac, Daniela de Barros Mucci, Amanda C. Cunha Figueiredo, Sophie E. Moore, Christian Mølgaard, Lindsay H. Allen, Kim F. Michaelsen   +15 more
openalex   +1 more source