Results 271 to 280 of about 1,240,536 (340)

Integrated 'omics analysis reveals human milk oligosaccharide biosynthesis programs in human lactocytes. [PDF]

iScience
Nyquist SK, Annepureddy LD, Sejane K, Furst A, Trahan GD, Rudolph MC, Twigger AJ, Bode L, Engelhardt BE, Martin Carli JF, Goods BA.   +10 more
europepmc   +1 more source

A Comparative Study of Infant Formulas and Human Milk: Exploring the Impact of Cow's Milk Consumption on Beneficial Fatty Acids as trans-vaccenic (trans-C18:1 n-7) in Breast Milk

Laura Sanjulián, Alexandre Lamas, Rocío Barreiro, Ismael Martínez, Leopoldo García-Alonso, Alberto Cepeda, C. Fente, Patricia Regal   +7 more
openalex   +2 more sources

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Unraveling Stage-Specific Metabolites in Human Milk and Their Links to Maternal Physiology: Insights from a Mexican Population. [PDF]

Nutrients
Zarzoza-Mendoza IC, Rodríguez-Cruz M, Carmona-Isunza MC, Sánchez-Vidal H, Páez-Franco JC, Luna-Guzmán CE, Morales-Marzana M, Domínguez-Salgado JM, Villa-Morales J, Barbosa-Cortés L.   +9 more
europepmc   +1 more source

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease

Advanced Science, EarlyView.
TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo, Hong Ni, Yu Lu, Zhengyu Cui, Yixing Wang, Zilu Zhu, Xinyu Wei, Chenyi Xia, Ming Xu, Lixia Du, Yufang Yang, Shi Shu, Ke Wang, Zhifei Wang, Chunlei Shan, Deheng Wang   +15 more
wiley   +1 more source

Selected Protective Mechanisms of Human Milk Against Intestinal Protozoal Infections in Infants. [PDF]

Curr Issues Mol Biol
Wróblewska J, Długosz A, Wróblewski M, Nuszkiewicz J, Sutkowy P, Woźniak A.   +5 more
europepmc   +1 more source

Tetrahydrocannabinol and breastfeeding: preliminary analysis of THC clearance in human milk

Miguel Sandonis, Rafael Álvarez, Maia Brik, A. Creus, Eduardo Sánchez, Josep Antoni Ramos‐Quiroga, Constanza Daigre   +6 more
openalex   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Optical and physical properties of human milk

Jean‐Pierre Wolf
openalex   +2 more sources

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source