Results 41 to 50 of about 260,495 (313)

The retinoblastoma protein/p16INK4A pathway but not p53 is disrupted by human papillomavirus in penile squamous cell carcinoma [PDF]

, 2011
Aims: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood. Human papillomavirus (HPV) may be involved in carcinogenesis, but few studies have compared cell-cycle protein expression in HPV positive and negative cancers.
Backes, Bezerra, Bleeker, Cubilla, Daling, De Vuyst, Eichten, Ferreux, Fife, Funk, Funk, Gargiulo, Gartel, Gregoire, Guerrero, Hafkamp, Koyamatsu, Lam, Lam, Lont, Lopes, Lu, Martins, Munoz, Nam, Narayana, Nevins, Pascual, Prowse, Robinson, Rubin, Sano, Senba, Shoji, Sobin, Stankiewicz, Trimble, Vousden, Yanagawa   +38 more
core   +3 more sources

Implementation of FTA Elute Card for Viral RNA Storage and Cost‐Effective Wastewater Surveillance

Advanced Sensor Research, EarlyView.
A strategy is developed for room‐temperature storage of RNA from wastewater using FTA Elute cards, which allow for easy and portable transportation. FTA Elude cards provided a 15.4% recovery of the original RNA with cards, compared to only 0.5% recovery without cards.
Qingxin Hui, Yuwei Pan, David Cullen, Zhugen Yang   +3 more
wiley   +1 more source

Frequent detection of high human papillomavirus DNA loads in oral potentially malignant disorders [PDF]

, 2016
Human papillomavirus (HPV) is estimated to be the cause of 40-80% of the squamous cell carcinoma of the oropharynx but only of a small fraction of the oral cavity cancers.
ANTONELLI, Guido, CANNELLA, FABIANA, Ciolfi, Chiara, GENTILE, Massimo, PALAIA, GASPARE, PIERANGELI, Alessandra, POLIMENI, Antonella, ROMEO, Umberto, RUSSO, CLAUDIA, SCAGNOLARI, CAROLINA, SCIANDRA, ILARIA   +10 more
core   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Proteomic identification of potential biomarkers for cervical squamous cell carcinoma and human papillomavirus infection

Tumor Biology, 2017
It is known that high-risk human papillomavirus infection is the main etiological factor in cervical carcinogenesis. However, human papillomavirus screening is not sufficient for early diagnosis.
Song Qing, Wuniqiemu Tulake, Mingfang Ru, Xiaohong Li, Reziwanguli Yuemaier, Dilare Lidifu, Aierken Rouzibilali, Axiangu Hasimu, Yun Yang, Reziya Rouziahong, Halmurat Upur, Abulizi Abudula   +11 more
doaj   +1 more source

Regulation of HPV transcription

Clinics, 2018
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on ...
Aline Lopes Ribeiro, Amanda Schiersner Caodaglio, Laura Sichero   +2 more
doaj   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Knowledge and attitudes of mothers toward HPV vaccination: A cross-sectional study in Kazakhstan

Women's Health, 2023
Background: Although recommended for all member states of World Health Organization, there is no national human papillomavirus vaccination program in Kazakhstan.
Aisha Babi, Torgyn Issa, Alpamys Issanov, Sholpan Akhanova, Natalya Udalova, Svetlana Koktova, Askhat Balykov, Zhanna Sattarkyzy, Balkenzhe Imankulova, Nazira Kamzayeva, Wassim Y. Almawi, Gulzhanat Aimagambetova   +11 more
doaj   +1 more source

A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis

Advanced Science, EarlyView.
This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao, Qiang Wen, Siyuan Qiao, Linyi Deng, Keyue Li, Zhuyan Shao, Xiaonan Liu, Tao Zhu, Chao Zhang, Da Han, Weihong Tan   +10 more
wiley   +1 more source

Human Papillomavirus (HPV) Vaccine: Attitudes, Behaviors, and Beliefs of At-Risk Women [PDF]

, 2008
Cervical cancer is primarily caused by human papillomavirus (HPV) and is the second most common cause of cancer-related mortality among women. Female college students may be at risk for contracting HPV based on their sexual behavior.
Caron, Rosemary M, Kispert, Elisabeth, McGrath, Robert J.   +2 more
core   +1 more source