Results 51 to 60 of about 260,495 (313)

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

Advanced Science, EarlyView.
CD161 is identified as a novel inhibitory receptor on bone marrow (BM)‐resident CD8⁺ T cells in multiple myeloma (MM). Through interaction with its ligand CLEC2D, CD161 impairs T‐cell function and promotes immune suppression. Blockade of CD161 restores tissue residency and cytotoxicity of CD8⁺ T cells and enhances chimeric antigen receptor T‐cell (CAR ...
Liwen Wang, Linzhi Xie, Yi Zhou, Shiming Tan, Yan Yu, Qin Zhang, Xuefeng Chen, Yuhan Yan, Ruiheng Luo, Han Xiao, Qian Cheng, Jian Zhang, Ying Li, Erhua Wang, Tiebin Jiang, Jing Liu, Xin Li   +16 more
wiley   +1 more source

Prevalence and genotype distribution of human papillomavirus infection among Kurdish people, Iran

SAGE Open Medicine
Background and aim: Human papillomavirus is a common sexually transmitted infection and a health concern, being the major cause of cervical cancer and genital warts.
Bahram Nikkhoo, Soma Mahmoodian, Pourya Bahrami, Arshia Daraee, Farzad Soleimani, Fatemeh Zamani, Sherko Nasseri, Khaled Rahmani   +7 more
doaj   +1 more source

Human papillomavirus E2 regulates SRSF3 (SRp20) to promote capsid protein expression in infected differentiated keratinocytes [PDF]

, 2016
The human papillomavirus (HPV) life cycle is tightly linked to differentiation of the infected epithelial cell suggesting a sophisticated interplay between host cell metabolism and virus replication.
Beemon, K. L., Bodily, J. M., Graham, S. V., Hernandez-Lopez, H., Klymenko, Tetyana, MacDonald, A. I.   +5 more
core   +2 more sources

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

Advanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen, Yuexuan Xu, Ying Xu, Xiao Liu, Yuting Zhang, Dan Ye, Sai Han, Shili Liu, Youzhong Zhang   +8 more
wiley   +1 more source

Oral human papillomavirus in men who have sex with men in Latin America: a review [PDF]

World Cancer Research Journal
Objective: Men who have sex with men run a high risk of oral human papillomavirus, and studies have investigated its prevalence in Latin America.
M. Guapillo-Vargas, J. Jaramillo-Vázquez, B. Cerda-Cristerna   +2 more
doaj   +1 more source

Human Papillomavirus among Women Undergoing Papanicolaou Smear Test in the Department of Gynaecologic Oncology of a Tertiary Care Centre

Journal of Nepal Medical Association, 2023
Introduction: In invasive cervical specimens or precursors, high-risk human papillomavirus Deoxyribonucleic acid may be detected to identify females at risk of developing cervical cancer.
Mahendra Raj Shrestha, Ajaya Basnet, Rajendra Maharjan, Sagar Ghimire, Nisha Khatri, Arju Shrestha, Lochan Karki, Saujanya Karmacharya   +7 more
doaj   +1 more source

History of Cervical Cancer and the Role of the Human Papillomavirus, 1960-2000 [PDF]

, 2009
Annotated and edited transcript of a Witness Seminar held on 13 May 2008. Introduction by Professor Anne M Johnson, Division of Population Health and Institute for Global Health, UCL.
Reynolds, LA, Tansey, EM
core  

Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism [PDF]

, 2009
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantable tumours in testing the efficacy of vaccines.
Germain J. Fernando, Jie Zhong, Marion E. G. Brunck, Xiao Song Liu   +3 more
core   +2 more sources

BRIGHT Enables High‐SNR Live‐Cell Imaging of Non‐Repetitive Sequences via Bivalent Fluorescent Nanobody‐Mediated Cascade‐Dependent Illumination

Advanced Science, EarlyView.
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng, Tao Huang, Yanxi Han, Meng Tian, Duo Wang, Zilong Mei, Yu Ma, Yingshuo Ma, Jinming Li, Rui Zhang   +9 more
wiley   +1 more source

Human papillomavirus infection and cervical cancer precursor lesions in women living by Amazon rivers: investigation of relations with markers of oxidative stress

Einstein (São Paulo)
Objective To investigate the relation between oxidative stress markers, human papillomavirus infection and cervical cancer precursor lesions. Methods The study comprised women aged 14 to 60 years living in communities located by Amazon rivers in the ...
Bruna Emanuelle Sanches Borges, Elza Baia de Brito, Hellen Thais Fuzii, Cláudia Simone Baltazar, Aline Barreto Sá, Camile Irene Mota da Silva, Gleyce de Fátima Silva Santos, Maria da Conceição Nascimento Pinheiro   +7 more
doaj   +1 more source