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Protective antibodies against human parainfluenza virus type 3 infection [PDF]

open access: yesmAbs, 2021
Human parainfluenza virus type III (HPIV3) is a common respiratory pathogen that afflicts children and can be fatal in vulnerable populations, including the immunocompromised. There are currently no effective vaccines or therapeutics available, resulting
Jim Boonyaratanakornkit   +10 more
doaj   +2 more sources

Modeling Infection and Tropism of Human Parainfluenza Virus Type 3 in Ferrets [PDF]

open access: yesmBio, 2022
Human parainfluenza virus type 3 (HPIV-3) is a significant cause of lower respiratory tract infections, with the most severe disease in young infants, immunocompromised individuals, and the elderly.
Laurine C. Rijsbergen   +11 more
doaj   +2 more sources

A fatal case of neonatal viral sepsis caused by human parainfluenza virus type 3 [PDF]

open access: yesVirology Journal, 2023
Background Sepsis is a systemic inflammatory response syndrome caused by severe infection in children, but cases of sepsis associated with human parainfluenza virus (HPIV) have been rarely reported in newborns.
Xiangpeng Chen   +10 more
doaj   +2 more sources

Evaluation of Human Respiratory Syncytial Virus and Human Parainfluenza Virus Type 3 among Hospitalized Children in Northwest of Iran [PDF]

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2021
Background. Acute respiratory tract infections (ARTIs) are the leading cause of illnesses in children. Human respiratory syncytial virus (HRSV) and human parainfluenza viruses (HPIVs) are among the most common etiologic agents associated with viral ...
Zahra Ramezannia   +6 more
doaj   +2 more sources

Human parainfluenza virus surveillance in pediatric patients with lower respiratory tract infections: a special view of parainfluenza type 4

open access: yesJornal de Pediatria (Versão em Português), 2018
Objective: Characterize the role of human parainfluenza virus and its clinical features in Brazilian children under 2 years of age presenting with acute lower respiratory tract infections.
Luciano M. Thomazelli   +6 more
doaj   +7 more sources

Vimentin inhibits α-tubulin acetylation via enhancing α-TAT1 degradation to suppress the replication of human parainfluenza virus type 3. [PDF]

open access: yesPLoS Pathogens, 2022
We previously found that, among human parainfluenza virus type 3 (HPIV3) proteins, the interaction of nucleoprotein (N) and phosphoprotein (P) provides the minimal requirement for the formation of cytoplasmic inclusion bodies (IBs), which are sites of ...
Pengfei Liu   +5 more
doaj   +2 more sources

Virion-Associated Cholesterol Regulates the Infection of Human Parainfluenza Virus Type 3 [PDF]

open access: yesViruses, 2019
The matrix (M) proteins of paramyxoviruses bind to the nucleocapsids and cytoplasmic tails of glycoproteins, thus mediating the assembly and budding of virions.
Qiaopeng Tang   +3 more
doaj   +2 more sources

Environmental lag effects and clinical characteristics of pediatric human parainfluenza virus type 3 infections [PDF]

open access: yesScientific Reports
Human parainfluenza virus type 3 (HPIV3) is a major cause of severe pediatric respiratory infections in infants, but its association with meteorological factors is not fully understood.
Dan Hong   +7 more
doaj   +2 more sources

Human Parainfluenza Virus Type 3 in Wild Nonhuman Primates, Zambia [PDF]

open access: yesEmerging Infectious Diseases, 2013
Human parainfluenza virus type 3 (HPIV3) genome was detected in 4 baboons in Zambia. Antibody for HPIV3 was detected in 13 baboons and 6 vervet monkeys in 2 distinct areas in Zambia.
Michihito Sasaki   +10 more
doaj   +2 more sources

PI4KB on Inclusion Bodies Formed by ER Membrane Remodeling Facilitates Replication of Human Parainfluenza Virus Type 3 [PDF]

open access: yesCell Reports, 2019
Summary: Many positive-strand RNA viruses remodel the endomembrane to form specialized replication organelles. However, knowledge regarding whether negative-strand RNA viruses take advantage of intracellular membranes for replication is limited.
Zhifei Li   +3 more
doaj   +2 more sources

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