Results 151 to 160 of about 11,822,869 (333)

Human physiology

HUMAN PHYSIOLOGY Human physiology (-
Walker, Kenneth
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The physiological and pharmacological actions and fate of several sympathomimetic amines in vascular beds

, 1971
165 leavesThesis (M.D.) -- University of Adelaide, Dept.
Jellett, Leon Barry
core  

Approaches in line with human physiology to prevent skin aging. [PDF]

Front Physiol, 2023
Karimi N.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Muscle cell membranes and chloride ions

, 1970
Thesis (Ph.D.) -- University of Adelaide, Dept.
Bretag, Allan Hugo
core  

The uptake and metabolism of noradrenaline by the rabbit uterus [PDF]

, 1978
xiii, 159 leaves : tables ; 30 cm.Thesis (Ph.D.)--University of Adelaide, Dept.
Kennedy, Jennifer Ann
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Hepatotoxicity of chemicals in isolated hepatocytes [PDF]

, 1978
vi, 237 leaves : photos., tables, graphs ; 30 cm.Thesis (Ph.D.)--University of Adelaide, Dept.
Stacey, Neill Hubert
core  

LIMK2: A Multifaceted kinase with pleiotropic roles in human physiology and pathologies. [PDF]

Cancer Lett, 2023
Shah K, Cook M.
europepmc   +1 more source