Results 171 to 180 of about 1,669,866 (339)

Editorial: Rhythmic Patterns in Neuroscience and Human Physiology. [PDF]

Front Hum Neurosci, 2022
Dominici N, Iosa M, Vannozzi G, De Bartolo D.   +3 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Urine cf-nucleosomes: A non-invasive window into human physiology and disease. [PDF]

Cell Genom
Lotem M, Sharkia I, Azria B, Harpenas E, Ormianer M, Rosen H, Falick-Michaeli T, Friedman N.   +7 more
europepmc   +2 more sources

Independent effects of acute normobaric hypoxia and hypobaric hypoxia on human physiology. [PDF]

Sci Rep, 2022
Rosales AM, Shute RJ, Hailes WS, Collins CW, Ruby BC, Slivka DR.   +5 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Leftovers of viruses in human physiology. [PDF]

Brain Struct Funct, 2021
Arneth B.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Read !Book Human Anatomy & Physiology Laboratory Manual, Cat Version (13th Edition) *Full Online

, 2020
Read !Book Human Anatomy & Physiology Laboratory Manual, Cat Version (13th Edition) *Full Online
openalex   +1 more source

Near isogenic lines (NIL) of sorghum carrying wild type or waxy alleles of the granule-bound starch synthase (GBSS) gene have distinct effects on human gut microbiome phenotypes and host physiological characteristics [PDF]

, 2022
Qinnan Yang, Mallory J. Van Haute, Nate Korth, Scott E. Sattler, Devin J. Rose, Anthony F. Juritsch, Jing Shao, Kristin A Beede, Robert Schmaltz, Jeff Price, J. J. Toy, Amanda E. Ramer‐Tait, Andrew K. Benson   +12 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source