Results 81 to 90 of about 128,366 (181)

Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundCardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model.
Xiao‐Xu Qiu   +12 more
doaj   +1 more source

Pluripotent Stem Cells: Current Understanding and Future Directions

open access: yesStem Cells International, 2016
Pluripotent stem cells have the ability to undergo self-renewal and to give rise to all cells of the tissues of the body. However, this definition has been recently complicated by the existence of distinct cellular states that display these features ...
Antonio Romito, Gilda Cobellis
doaj   +1 more source

Pluripotency and its layers of complexity

open access: yesCell Regeneration, 2012
Pluripotency is depicted by a self-renewing state that can competently differentiate to form the three germ layers. Different stages of early murine development can be captured on a petri dish, delineating a spectrum of pluripotent states, ranging from ...
Jolene Ooi, Pentao Liu
doaj   +1 more source

Establishment and characterization of induced pluripotent stem cells from placental mesenchymal stromal cells

open access: yesStem Cell Research, 2018
Human term placenta is a bulky organ which harbours abundant mesenchymal stromal cells. This study reports isolation and characterization of placental mesenchymal stromal cells (PMSCs) followed by reprogramming of PMSCs to induced pluripotent stem cells (
Shagufta Parveen
doaj   +1 more source

Search for naïve human pluripotent stem cells

open access: yesWorld Journal of Stem Cells, 2015
Normal mouse pluripotent stem cells were originally derived from the inner cell mass (ICM) of blastocysts and shown to be the in vitro equivalent of those pre-implantation embryonic cells, and thus were called embryonic stem cells (ESCs). More than a decade later, pluripotent cells were isolated from the ICM of human blastocysts.
Simone Aparecida Siqueira, Fonseca   +2 more
openaire   +2 more sources

Generation of stem cell-derived β-cells from patients with type 1 diabetes

open access: yesNature Communications, 2016
Pancreatic β cells can be generated from pluripotent stem cells. Here, the authors show that human induced pluripotent stem cells from patients with type 1 diabetes can be differentiated into β-like cells that have no detectable differences compared with
Jeffrey R. Millman   +5 more
doaj   +1 more source

Comprehensive insight into chicken germline cells: A review

open access: yesPoultry Science
Genetic information is propagated in the progeny through germ cells. The stem cells which are precursors of these germ cells have the ability of self-renewal and can give rise to pluripotent stem cells under favorable conditions.
Malik Ahsan Ali   +4 more
doaj   +1 more source

Repeated pluripotent stem cell administration delays age-associated decline in mice

open access: yesJournal of Animal Reproduction and Biotechnology
Background: Yamanaka-factor-mediated partial reprogramming can reverse selected age-associated changes without complete loss of cellular identity. We asked whether repeated systemic administration of intact human pluripotent stem cells, which maintain ...
Sae-Byeok Hwang   +3 more
doaj   +1 more source

Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

open access: yesStem Cells and Cloning: Advances and Applications, 2009
Brad B Swelstad, Candace L KerrInstitute for Cell Engineering, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MA, USAAbstract: Pluripotent stem cells have been derived from various embryonic, fetal and adult sources ...
Brad B Swelstad, Candace L Kerr
doaj  

History of Pluripotent Stem Cells and Human Naïve Pluripotent Stem Cells

open access: yesCytometry Research, 2017
Ueda, Mai, Takashima, Yasuhiro
openaire   +1 more source

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