Results 41 to 50 of about 491,966 (291)

The influence of team motivational climate on employee creativity—mediating role of domain-relevant skills

Frontiers in Psychology, 2023
Employee creativity drives enterprise development, and team motivational climate plays an important role in incubating employee creativity. Based on creativity component theory, this study explores the impact of team motivational climate (mastery climate
Yanmei Zhao, Ting Yu, Zhengtang Zhang
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Green Training and Development Practices on Environmental Sustainability: Evidence from Wamco PLC

Journal of Interdisciplinary Socio Economic and Community Study, 2022
Green training and development practices have been acknowledged as veritable tools for addressing environmental challenges; it is also a key ingredient for promoting the acceptance of environmental conservation in the workplace because in the long run ...
Tinuke Moradeke Fapohunda, Kabiru Ishola Genty, Lateef Okikiola Olanipekun   +2 more
doaj   +1 more source

Human resources management system for Higher Education institutions [PDF]

arXiv, 2021
In an environment where employees and their experience are of central value to the company, human resources management (HRM) represents a significant aspect of business efficiency. In this paper we present a model of an HRM information system for universities. Special attention is paid to aspects of the system that support processes specific to science
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Indian husbands’ support of their wives’ upward mobility in corporate South Africa: Wives’ perspectives

SA Journal of Industrial Psychology, 2016
Orientation: Spousal support is a crucial area to explore, particularly due to the increased prevalence of dual-career couples in South Africa and the dynamics facing them.
Sumaiyah F. Ahmed, Nasima M.H. Carrim
doaj   +1 more source

Toward a normative theory of (self-)management by goal-setting [PDF]

arXiv, 2023
People are often confronted with problems whose complexity exceeds their cognitive capacities. To deal with this complexity, individuals and managers can break complex problems down into a series of subgoals. Which subgoals are most effective depends on people's cognitive constraints and the cognitive mechanisms of goal pursuit.
arxiv  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Gen Z’s enduring commitment to fitness apps: a comprehensive examination

Cogent Business & Management
This study investigates the sustained engagement of Generation Z with fitness apps using the Theory of Consumption Values (TCV) to identify the key determinants influencing this behaviour.
Vinod Sharma, Vaishali Mahajan, Manohar Kapse, Aakash H. Karhale, Sagar Surwade   +4 more
doaj   +1 more source