Results 51 to 60 of about 2,173,611 (355)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Gen Z’s enduring commitment to fitness apps: a comprehensive examination
Cogent Business & ManagementThis study investigates the sustained engagement of Generation Z with fitness apps using the Theory of Consumption Values (TCV) to identify the key determinants influencing this behaviour.
Vinod Sharma +4 more
doaj +1 more source
Procedural Justice in Selection from the Lens of Psychological Contract Theory
Organizacija, 2020 Background and purpose: In recruitment and selection, job applicants do not only base their justice judgment on the actual experience but also compare what happens and what they expect.
Huy Phuong Tran +3 more
doaj +1 more source
PERANAN PRAKTEK-PRAKTEK MANAJEMEN MANUSIA PADA KINERJA OPERASIONAL : PENGENALAN PADA LINTAS NEGARA DAN INDUSTRI [PDF]
, 2004 The human resource management practices strategically become an attractive topic to be reviewed, from some research that had been done before, it was known that human resource management practices had great influences to the whole organizational ...
Dharmasetiawan, Noviati Kresna +1 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Best Practices in Diversity Management [PDF]
, 2001 [Excerpt] The International Personnel Management Association (IPMA) has undertaken a human resource benchmarking project with the National Association of State Personnel Executives (NASPE).
Reichenberg, Neil E
core +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
SA Journal of Industrial Psychology, 2016 Orientation: Spousal support is a crucial area to explore, particularly due to the increased prevalence of dual-career couples in South Africa and the dynamics facing them.
Sumaiyah F. Ahmed, Nasima M.H. Carrim
doaj +1 more source
FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source