Results 101 to 110 of about 3,768,967 (359)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

The Basic Methodical Approaches to the Organization of Trainings of the Specialized Anti-Epidemic Teams from Irkutsk Antiplague Institute

Эпидемиология и вакцинопрофилактика, 2015
The basic methodical approaches to the organization of trainings of the specialized anti-epidemic teams in the most approximate conditions to real extraordinary event are described. These trainings purpose the support of operative readiness of the mobile
A. K. Noskov, V. A. Vishnyakov, M. V. Chesnokova, S. A. Kosilko, S. A. Belkova, L. M. Mikhailov, S. V. Balakhonov   +6 more
doaj   +1 more source

Human Rights in the United Nations [PDF]

, 1964
Myres S. McDougal, Gerhard Bebr
openalex   +1 more source

Human Rights and Fundamental Rights

SSRN Electronic Journal
A crescente consciencialização da ligação entre proteção e preservação do ambiente e realização de direito humanos e fundamentais tem levado a que, desde a década de 1970, se tenha assistido a um processo de greening do catálogo tradicional de direitos humanos e fundamentais – identificando obrigações ambientais ao abrigo de direitos humanos e ...
Rocha, Armando, Oliveira, Heloísa
openaire   +3 more sources

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Human Rights [PDF]

, 2020
Buyse, A., Glasius, M.
openaire   +6 more sources

Comparative Evaluation of Proteolytic and Superoxide Dismutase Activities of Yersinia pestis Strains with Different Plasmid imposition

Эпидемиология и вакцинопрофилактика, 2015
Data of the proteolytic and superoxide dismutase activities of Yersinia pestis strains with different plasmid spectrum are presented. It was established that superoxide dismutase activity of the tested Y.
O. V. Yur’Eva, V. I. Dubrovina, G. B. Mukhturgin, T. A. Ivanova, K. M. Korytov, E. G. Tokmakova, S. V. Balakhonov   +6 more
doaj   +1 more source

Human Rights in Global Health Governance [PDF]

, 2018
Human rights frame global health governance. In codifying a normative foundation for global governance in the aftermath of World War II, states came together under the auspices of an emergent United Nations (UN) to develop human rights under ...
Gostin, Lawrence O., Huffstetler, Hanna, Meier, Benjamin Mason   +2 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source