Results 81 to 90 of about 9,207,117 (308)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Guiding Principles on Business and Human Rights

Social Science Research Network, 2023
Nicolas Bueno, C. Kaufmann
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Human Rights Watch

The Fairchild Books Dictionary of Fashion, 2022
A. Ganesan, Sarah Leah Whitson, Kanae Doi, Meenakshi Ganguly, Karen Ackman, Jorge Castañeda, Tony Elliott, Michael G. Fisch, M. E. Gellert, Barry Meyer, Aoife O’Brien, Joan R. Platt, A. Rao, Neil Rimer, Victoria Riskin, Amy L. Robbins, G. Robeson, S. Rubin, Kevin P. Ryan, Jean-Louis Servan-Schreiber, J. Solana, Siri Stolt-Nielsen, Darian W. Swig, John R. Taylor, Jonathan F. Fanton   +24 more
semanticscholar   +1 more source

Povrede prava zajamčenih Europskom konvencijom za zaštitu ljudskih prava i temeljnih sloboda utvrđene u području upravnog prava u Republici Hrvatskoj – izabrane presude Europskog suda za ljudska prava

Zbornik Pravnog Fakulteta Sveučilišta u Rijeci
Sustav zaštite ljudskih prava uspostavljen Europskom konvencijom za zaštitu ljudskih prava i temeljnih sloboda ostvaruje se kroz nadležnost Europskog suda za ljudska prava da ispituje pojedinačne zahtjeve u kojima se podnositelji žale na povrede ...
Zvonimir Mataga, Franka Viljac Herceg
doaj   +1 more source

The State’s obligation to regulate and monitor private health care facilities: the Alyne da Silva Pimentel and the Dzebniauri cases

Public Health Reviews, 2017
The Human Rights in Patient Care framework embraces general human rights principles applicable to both patients and health care providers in the delivery of health care.
Ximena Andión Ibañez, Tamar Dekanosidze   +1 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Margin of Appreciation and Incrementalism in the Case Law of the European Court of Human Rights

Human Rights Law Review, 2018
Fundamental rights standards in Europe diverge as a result of differences in legal traditions, constitutional values and historical developments. The European Court of Human Rights therefore faces the challenge of having to balance the need for uniform ...
J. Gerards
semanticscholar   +1 more source

The Basic Methodical Approaches to the Organization of Trainings of the Specialized Anti-Epidemic Teams from Irkutsk Antiplague Institute

Эпидемиология и вакцинопрофилактика, 2015
The basic methodical approaches to the organization of trainings of the specialized anti-epidemic teams in the most approximate conditions to real extraordinary event are described. These trainings purpose the support of operative readiness of the mobile
A. K. Noskov, V. A. Vishnyakov, M. V. Chesnokova, S. A. Kosilko, S. A. Belkova, L. M. Mikhailov, S. V. Balakhonov   +6 more
doaj   +1 more source