Results 11 to 20 of about 493,813 (294)

Interaction of Citrinin with Human Serum Albumin [PDF]

Toxins, 2015
Citrinin (CIT) is a mycotoxin produced by several Aspergillus, Penicillium, and Monascus species. CIT occurs worldwide in different foods and drinks and causes health problems for humans and animals.
Miklós Poór, Beáta Lemli, Mónika Bálint, Csaba Hetényi, Nikolett Sali, Tamás Kőszegi, Sándor Kunsági-Máté   +6 more
doaj   +4 more sources

Mathematical modeling of interactions of cabergoline with human serum albumin for biosensing of human serum albumin

Sensing and Bio-Sensing Research, 2019
In this work, we are going to study the interactions of cabergoline (CBG) with human serum albumin (HSA) by mathematical modeling of voltammetric and spectroscopic data.
Ali R. Jalalvand, Sirous Ghobadi, Vali Akbari, Hector C. Goicoechea, Elahe Faramarzi, Majid Mahmoudi   +5 more
doaj   +4 more sources

Photoprogramming Allostery in Human Serum Albumin [PDF]

Bioconjugate Chemistry, 2018
Developing strategies to interfere with allosteric interactions in proteins not only promises to deepen our understanding of vital cellular processes but also allows their regulation using external triggers. Light is particularly attractive as a trigger being spatiotemporally selective and compatible with the physiological environment.
Rindia M. Putri, Habiburrahman Zulfikri, Jean Wilfried Fredy, Alberto Juan, Pichayut Tananchayakul, Jeroen J. L. M. Cornelissen, Melissa S. T. Koay, Claudia Filippi, Nathalie Katsonis   +8 more
openaire   +4 more sources

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

A Narrative Literature Review of the Established Safety of Human Serum Albumin Use as a Stabilizer in Aesthetic Botulinum Toxin Formulations Compared to Alternatives

Toxins, 2023
Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum
Sonja Sattler, Stephen Gollomp, Andrew Curry   +2 more
doaj   +1 more source

The Influence of Oxidative Stress on Serum Albumin Structure as a Carrier of Selected Diazaphenothiazine with Potential Anticancer Activity

Pharmaceuticals, 2021
Albumin is one of the most important proteins in human blood. Among its multiple functions, drug binding is crucial in terms of drug distribution in human body.
Małgorzata Maciążek-Jurczyk, Beata Morak-Młodawska, Małgorzata Jeleń, Wiktoria Kopeć, Agnieszka Szkudlarek, Aleksandra Owczarzy, Karolina Kulig, Wojciech Rogóż, Jadwiga Pożycka   +8 more
doaj   +1 more source

Absence of the CXCR4 antagonist EPI-X4 from pharmaceutical human serum albumin preparations

Journal of Translational Medicine, 2021
Background Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a natural antagonist of the CXC chemokine receptor 4 (CXCR4). EPI-X4 is a 16-mer peptide that is released from human serum albumin (HSA) by acidic aspartic proteases such as Cathepsin D and E ...
Andrea Gilg, Mirja Harms, Lia-Raluca Olari, Ann-Kathrin Urbanowitz, Halvard Bonig, Jan Münch   +5 more
doaj   +1 more source

Binding of glycyrrhizin of human serum and human serum albumin.

Chemical and Pharmaceutical Bulletin, 1989
The binding of glycyrrhizin (GLZ) to human serum and human serum albumin (HSA) was examined by an ultrafiltration technique. Specific and nonspecific bindings were observed in both human serum and HSA. The association constants (K) for the specific bindings were very similar: 1.31 x 10(5) M-1 in human serum and 3.87 x 10(5) M-1 in HSA.
Yoko Sakiya, Tsutomu Ichikawa, Shoji Awazu, Shiro Ishida, Masahiro Kinoshita   +4 more
openaire   +4 more sources

Overview of Albumin and Its Purification Methods [PDF]

Advanced Pharmaceutical Bulletin, 2016
As the most frequent plasma protein, albumin constitutes more than 50% of the serum proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is known as a versatile protein carrier for transportation of various endogenous
Ramin Raoufinia, Ali Mota, Neda Keyhanvar, Fatemeh Safari, Sara Shamekhi, Jalal Abdolalizadeh   +5 more
doaj   +1 more source

A Comprehensive Spectroscopic Analysis of the Ibuprofen Binding with Human Serum Albumin, Part II

Scientia Pharmaceutica, 2021
Human serum albumin (HSA) is the most abundant human plasma protein. HSA plays a crucial role in many binding endos- and exogenous substances, which affects their pharmacological effect.
Anna Ploch-Jankowska, Danuta Pentak, Jacek E. Nycz   +2 more
doaj   +1 more source