Results 31 to 40 of about 38,215 (244)

Cellular tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) [PDF]

Retrovirology, 2011
Background HTLV-1 predominantly transforms CD4+T cells in vitro and induces leukemia and neurological disease in vivo, whereas HTLV-2 shows a preference for CD8+T cell transformation in vitro with limited in vivo pathology. To better understand cellular tropism of HTLV-1 and HTLV-2 early after in vivo infection we determined proviral load and gene ...
Green Patrick L, Doueiri Rami, Yin Han, Kannian Priya   +3 more
doaj   +2 more sources

Human T-lymphotropic virus type 2 subtype b in a patient with chronic neurological disorder [PDF]

Journal of NeuroVirology, 2014
Human T-cell lymphotropic virus is a retrovirus described worldwide. There are four HTLV types: HTLV-1 to 4. Only HTLV-1 and 2 are linked to human disease. The majority of infected individuals remain asymptomatic. However, it is estimated that 5 % of HTLV-1-infected patients present a clinical neurological disorder called HTLV-1-associated myelopathy ...
Carolina, Rosadas, Ana C P, Vicente, Louise, Zanella, Mauro J, Cabral-Castro, José M, Peralta, Marzia, Puccioni-Sohler   +5 more
openaire   +2 more sources

Phosphonated Carbocyclic 2'-Oxa-3'-azanucleosides as New Antiretroviral Agents [PDF]

, 2007
Phosphonated carbocyclic 2¢-oxa-3¢-azanucleosides have been synthesized and tested for their antiretroviral activity. The obtained results have shown that some of the compounds were as powerful as azydothymidine in inhibiting the reverse transcriptase ...
Balestrieri, E, Borrello, L, Chiacchio, U, Iannazzo, D, Macchi, B, Mastino, A, Piperno, A, Rescifina, A, Romeo, G, Romeo, R, Sciortino, M   +10 more
core   +1 more source

Prevalence of residual risks of the transfusion-transmitted infections in Riyadh hospitals: A two-year retrospective study

Open Chemistry, 2023
This study aimed to evaluate the prevalence and trends of transfusion-transmitted infections (TTIs) in two hospitals in Riyadh, as well as to judge the best type of tests to ensure blood transfusion safety. By using serological and nucleic acid test (NAT)
Mubaraki Murad A., Almuayrifi Hussain A., Hafiz Taghreed A., Alyousef Abdulaziz, Dkhil Mohamed A., Thagfan Felwa A., Abdel-Gaber Rewaida, Al-Najjar Mohammad A. A., Alkhudhayri Abdulsalam, Elshanat Sherif   +9 more
doaj   +1 more source

Short Communication: Current Prevalence and Risk Factors Associated with Human T Lymphotropic Virus Type 1 and Human T Lymphotropic Virus Type 2 Infections Among HIV/AIDS Patients in São Paulo, Brazil [PDF]

AIDS Research and Human Retroviruses, 2015
During the 1990s, high prevalences of HIV/human T lymphotropic virus type 1 (HTLV-1) and HIV/human T lymphotropic virus type 2 (HTLV-2) coinfections were detected in São Paulo, Brazil in association with intravenous drug use (IDU). The current prevalences and risk factors for HIV/HTLV-1/-2 were evaluated in 1,608 patients attending the AIDS/STD ...
Adele, Caterino-de-Araujo, Cláudio Tavares, Sacchi, Maria Gisele, Gonçalves, Karoline Rodrigues, Campos, Mariana Cavalheiro, Magri, Wong Kuen, Alencar   +5 more
openaire   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas, Hoelzer, Dieter (Prof. Dr.), Hummel, Michael, Schwartz, Stefan, Thiel, Eckhard   +4 more
core   +2 more sources

Loss of correlation between HIV viral load and CD4+ T-cell counts in HIV/HTLV-1 co-infection in treatment naive Mozambican patients [PDF]

, 2009
Seven hundred and four HIV-1/2-positive, antiretroviral therapy (ART) naïve patients were screened for HTLV-1 infection. Antibodies to HTLV-1 were found in 32/704 (4.5%) of the patients.
Augusto, O, Bhatt, N B, Bila, D, Di Mattei, P, Garsia, R, Gudo, E S, Jani, I V, Semá, C   +7 more
core   +2 more sources

Seroprevalence of HTLV-1/2 among blood donors in the state of Maranhao, Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2014
Background: Infection with human T-lymphotropic virus 1 or 2 (HTLV-1/2) is a major health problem. There is a public health policy defining measures for state hematology and hemotherapy centers in Brazil, in order to avoid virus transmission through ...
Graca Maria de Castro Viana, Maria do Desterro Soares Brandao Nascimento, Rodrigo Artur Souza de Oliveira, Alessandro Carvalho dos Santos, Carolina de Souza Galvao, Marcos Antonio Custodio Neto da Silva   +5 more
doaj   +1 more source

High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]

, 2015
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain, A Gessain, AH Smith, AM Vine, CR Bangham, D Weycker, E Gotuzzo, EL Murphy, F Okada, Graham P Taylor, H Kawai, H Merle, H Nakamura, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, J Crofton, JR Orland, K Nishioka, L Einsiedel, L Einsiedel, L Einsiedel, L LaGrenade, M Nagai, M Nakagawa, M Osame, M Sugimoto, M Sugimoto, MA Demontis, MG Flynn, OS Morgan, PJ McShane, S Mita, S Mori, Shohreh Honarbakhsh, T Arakaki, T Kondo, T Matsuda, T Yamashiro, W Matsuyama   +37 more
core   +1 more source