Results 151 to 160 of about 75,155 (200)

A presumed mouse parvovirus with overlooked high toxicity for human primitive CD34⁺ hematopoietic precursors <i>in vitro</i> and in bone marrow-humanized mice. [PDF]

Microbiol Spectr
Segovia JC, Ramírez JC, Río P, Lotufo CM, López-Bueno A, Calvo-López T, Lamana ML, Sandonís V, Balas A, Bautista JM, Abad P, Azcárate IG, Lopez Lorenzo JL, Jalilian FA, Amini R, Kinnunen PM, Jokelainen P, Mohanraj U, Söderlund-Venermo M, Almendral JM.   +19 more
europepmc   +1 more source

Diastolic Dysfunction with Vascular Deficits in HIV-1-Infected Female Humanized Mice Treated with Antiretroviral Drugs. [PDF]

Int J Mol Sci
Alomar FA, Dash PK, Ramasamy M, Venn ZL, Bidasee SR, Zhang C, Hackfort BT, Gorantla S, Bidasee KR.   +8 more
europepmc   +1 more source

17(R)-Resolvin D1 protects against sickle cell-related inflammatory cardiomyopathy in humanized mice.

Blood
Federti E, Mattoscio D, Recchiuti A, Matte A, Monti M, Cozzolino F, Iezzi M, Ceci M, Ghigo A, Tolosano E, Siciliano A, Ceolan J, Riccardi V, Gremese E, Brugnara C, De Franceschi L.   +15 more
europepmc   +1 more source

Humanized Mice as a Tool to Study Sepsis—More Than Meets the Eye

International Journal of Molecular Sciences, 2021
(1) Background. Repetitive animal studies that have disappointed upon translation into clinical therapies have led to an increased appreciation of humanized mice as a remedy to the shortcomings of rodent-based models.
, Laudanski Krzysztof
exaly   +2 more sources

Humanized mice in translational biomedical research

Nature Reviews Immunology, 2007
The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we
Leonard D Shultz, Fumihiko Ishikawa, Shultz Leonard D   +2 more
exaly   +1 more source

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Mice With Human Livers

Gastroenterology, 2013
Animal models are used to study many aspects of human disease and to test therapeutic interventions. However, some very important features of human biology cannot be replicated in animals, even in nonhuman primates or transgenic rodents engineered with human genes.
Markus, Grompe, Stephen, Strom
openaire   +2 more sources

Disorganization in mice and humans

American Journal of Medical Genetics, 2001
Disorganization (Ds) is an autosomal dominant mouse mutant that produces a remarkable array of birth defects. So variable is the phenotype that no two mice appear identical. Ds also has markedly reduced penetrance, with 85-99% of Ds mice having no apparent anomalies. Paired structures are often affected, but always asymmetrically.
N H, Robin, J H, Nadeau
openaire   +2 more sources

Biozzi mice: Of mice and human neurological diseases

Journal of Neuroimmunology, 2005
In 1972 Guido Biozzi selectively bred mice to study the immunopathological mechanisms underlying polygenic diseases. One line, the Biozzi antibody high (AB/H) mouse (now designated the ABH strain) was later found to be highly susceptible to many experimentally induced diseases such as autoimmune encephalomyelitis, autoimmune neuritis, autoimmune ...
Amor, S, Smith, PA, Hart, Boris, Baker, D   +3 more
openaire   +3 more sources