Results 171 to 180 of about 75,155 (200)

Human Tumours grown in Mice

Nature New Biology, 1972
INVESTIGATION of a tumour system requires a ready supply of tissue and ability to manipulate the growing environment. In vivo methods of maintenance are preferred, because the tissue is morphologically similar to the original, the therapeutic: toxicity ratio of possible treatments can be assessed and agents affecting tumour growth indirectly by ...
openaire   +2 more sources

MeCP2 Dysfunction in Humans and Mice

Journal of Child Neurology, 2005
Rett syndrome is a leading cause of postnatal neurodevelopmental regression. Rett syndrome is caused by mutations in MECP2, the gene encoding methyl-CpG binding protein 2. In up to 96% of all classic cases, Rett syndrome cases are caused by mutations or deletions in MECP2.
openaire   +2 more sources

In Vivo Imaging in Humanized Mice

2008
The radiological modalities that are currently utilized as critical components in clinical medicine have also been adapted to small-animal imaging, among which are ultrasound imaging, X-ray computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).
H, Masuda, H J, Okano, T, Maruyama, Y, Yoshimura, H, Okano, Y, Matsuzaki   +5 more
openaire   +2 more sources

Modifier genes in mice and humans

Nature Reviews Genetics, 2001
An emerging theme of studies with spontaneous, engineered and induced mutant mice is that phenotypes often depend on genetic background, implying that genetic modifiers have a role in guiding the functional consequences of genetic variation. Understanding the molecular and cellular basis by which modifier genes exert their influence will provide ...
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Modeling Human Epilepsies in Mice

Epilepsia, 2001
Summary: Two categories of mouse models of human epilepsy are now contributing to the experimental analysis of inherited seizure disorders. The first type includes homologous genetic models arrived at in the classic way; the genes from human inherited epilepsy syndromes are cloned, and mice are recreated with functionally identical mutations.
openaire   +2 more sources

Of Mice and Men: The Human Sciences and the Humanities

The Hastings Center Report, 1980
openaire   +2 more sources

CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice

Proceedings of the National Academy of Sciences of the United States of America, 2023
Prasanta K Dash, Rafal Kaminski, Pietro Mancuso   +2 more
exaly  

New generation humanized mice for virus research: Comparative aspects and future prospects

Virology, 2013
Ramesh Akkina
exaly  

Of Mice and Humans

Neurology Now, 2010
openaire   +1 more source

Humanized Mice for the Study of Immuno-Oncology

Trends in Immunology, 2018
Philippe De La Rochere, Silvia Guil-Luna, Didier Decaudin   +2 more
exaly