Results 171 to 180 of about 68,397 (297)

Humanized Mouse Models for Transplant Immunology.

, 2016
Our understanding of the molecular pathways that control immune responses, particularly immunomodulatory molecules that control the extent and duration of an immune response, have led to new approaches in the field of transplantation immunology to induce
Greiner, D L, Brehm, M A, Shultz, Leonard D, Kenney, L L   +3 more
core  

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Novel Humanized Mouse Model for Steroid-Resistant Asthma. [PDF]

Allergy
Yamada S, Maruoka S, Toyoshima S, Kurosawa Y, Ozoe R, Kozu Y, Mizumura K, Okayama Y, Ito R, Gon Y.   +9 more
europepmc   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

Humanized Mouse Models of Epstein Barr Virus Infection. [PDF]

Curr Protoc
von Boxberg SG, Gehrmann K, Nopper SL, Romann L, Kösegi S, Münz C.   +5 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Humanized Mouse Models for Type 1 Diabetes. [PDF]

Curr Protoc
Serreze DV, Tousey-Pfarrer M, Racine JJ.
europepmc   +1 more source

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

Construction and application of a humanized mouse model for prostate cancer in immunotherapy. [PDF]

Cancer Immunol Immunother
Guo W, Li H, Zhao Y, Qin J, Meng H, Ge X, Zhang C, Shi C.   +7 more
europepmc   +1 more source

Humanized NSG mouse models for HIV/AIDS

, 2018
Chen, Z
core