Results 181 to 190 of about 68,397 (297)

Rational design of a genomically humanized mouse model for dominantly inherited hearing loss, DFNA9

: DFNA9 is a dominantly inherited form of adult-onset progressive hearing impairment caused by mutations in the COCH gene. COCH encodes cochlin, a crucial extracellular matrix protein.
Sels, Lize, Ponsaerts, Peter, van Wijk, Erwin, Venselaar, Hanka, Gommeren, Hanne, Verdoodt, Dorien, Szewczyk, Krystyna, De Backer, Evi, Van Rompaey, Vincent, Van Camp, Guy, de Vrieze, Erik, Broekman, Sanne, Aben, Fien   +12 more
core  

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Application of the humanized mouse model in research into SARS-CoV-2 infection (Review). [PDF]

Med Int (Lond)
Feng X, Wang Y, Li Y, Long J, Liu F, Yang H.   +5 more
europepmc   +1 more source

Extinction Debt Paid Off: The Demise of the European Polecat (Mustela putorius) in NE Iberia

Integrative Zoology, EarlyView.
We studied a vanishing polecat population for a decade, until its ultimate demise, using camera trap and roadkill data, landscape descriptors and dietary and toxicological analyses.Polecat favoured farmland and avoided forests and water bodies occupied by the invasive American mink.
Salvador Salvador, Roger Puig‐Gironès, Xavier Llopart, Santiago Palazón, Miguel Clavero   +4 more
wiley   +1 more source

Humanized Mouse Models as a Cellular Platform for Investigating Immune-Hormonal Crosstalk and Therapeutic Strategies in Menopause. [PDF]

Aging Cell
Chandimali N, Bae J, Cheong SH, Bak SG, Kim YY, Kim JS, Lee SJ.   +6 more
europepmc   +1 more source

Spectacle and Spy Stories: The 1954 Royal Commission on Espionage

Australian Journal of Politics &History, EarlyView.
ABSTRACT The Menzies government's 1954 royal commission, established to investigate Soviet espionage in Australia, is well known as the backdrop to the Labor Party split. It saw opposition leader H.V. Evatt's demise and ushered in an almost 20‐year period of Liberal Party governance.
Ebony Nilsson
wiley   +1 more source

Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a microbiota-humanized mouse model. [PDF]

Front Immunol
Smout J, Lesker TR, Hoenicke L, Ortiz D, Zou M, Kruse F, Pirr S, Willers M, Härtel C, Falk C, Torow N, Viemann D, Strowig T, Huehn J.   +13 more
europepmc   +1 more source

Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food

Allergy, EarlyView.
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger   +7 more
wiley   +1 more source

In vivo base editing rescues ADPKD in a humanized mouse model. [PDF]

Nat Commun
Cheng AS, Li LX, Zhou JX, Harris PC, Calvet JP, Li X.   +5 more
europepmc   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source