Results 261 to 270 of about 68,397 (297)
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Human and mouse disorders of pigmentation
Current Opinion in Genetics & Development, 2003Disorders of pigmentation were among the first genetic diseases ever recognized because of their visually striking clinical phenotypes, resulting from defects of pigmentary melanocytes. Recent years have seen remarkable progress in understanding these diseases, largely as a result of the systematic parallel study of human patients and inbred mice with ...
Richard A, Spritz +3 more
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Human and Mouse Gene Nomenclature
Current Protocols in Human Genetics, 2003AbstractStandard genetic nomenclature is necessary to help researchers, clinicians, and the public to access data on their genes of interest, and to communicate in a globally understood language of approved gene symbols. In both human and mouse, one unique symbol (acronym/abbreviation) and one name are assigned for each gene.
Hester, Wain, Sue, Povey, Lois, Maltais
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The genetics of G in human and mouse
Nature Reviews Neuroscience, 2001The g factor refers to the substantial overlap that exists between individual differences in diverse cognitive processes in humans. In this article, I argue that a mouse model of g could provide a powerful analytic tool for exploring cognitive processes that are linked functionally by genes.
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Hematology/Oncology Clinics of North America, 2007
Multiple myeloma (MM) remains incurable despite high-dose chemotherapy with stem cell support. There is need, therefore, for continuous efforts directed toward the development of novel rational-based therapeutics for MM, which requires a detailed knowledge of the mutations driving this malignancy.
Constantine S, Mitsiades +2 more
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Multiple myeloma (MM) remains incurable despite high-dose chemotherapy with stem cell support. There is need, therefore, for continuous efforts directed toward the development of novel rational-based therapeutics for MM, which requires a detailed knowledge of the mutations driving this malignancy.
Constantine S, Mitsiades +2 more
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Humanization of the Mouse Mammary Gland
2015Although mouse models have provided invaluable information on the mechanisms of mammary gland development, anatomical and developmental differences between human and mice limit full understanding of this fundamental process. Humanization of the mouse mammary gland by injecting immortalized human breast stromal cells into the cleared murine mammary fat ...
A, Wronski +2 more
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Mouse models of human evolution
Current Opinion in Genetics & Development, 2014The genotype-phenotype map of human evolution is difficult to access since humans cannot be crossed with other species. Most of the ∼20 million genetic changes that occurred since the human and the chimpanzee lineage split, are fixed and hence completely correlated with all phenotypic changes that occurred during human evolution.
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Human and mouse gonadal development
Differentiation, 2023Gerald R. Cunha, Laurence S. Baskin
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Mouse models of human diseases
Current Opinion in Biotechnology, 1991Cancer, poliomyelitis, Alzheimer's and Gaucher disease, a seemingly disparate array of disorders, have become the target of powerful genetic analysis and drug screening protocols, using mouse strains that have been genetically altered to serve as models for understanding the disease and for helping the patient.
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Current Protocols in Human Genetics, 1996
AbstractHomology relationships between human and mouse genomes are very useful for identifying human or mouse homologs of disease traits that have been mapped in the other species. Conservation of genomic organization in human and mouse has long been recognized; however, detailed systematic examination of these relationships on a genome‐wide scale has ...
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AbstractHomology relationships between human and mouse genomes are very useful for identifying human or mouse homologs of disease traits that have been mapped in the other species. Conservation of genomic organization in human and mouse has long been recognized; however, detailed systematic examination of these relationships on a genome‐wide scale has ...
openaire +2 more sources