Results 271 to 280 of about 68,397 (297)

Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse

Xenobiotica, 2021
Maki Miyamoto, Yohei Kosugi, Ikumi Chisaki   +2 more
exaly  

[The mouse model and human disease].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004
The mouse is an ideal model organism for studies of human disease, because mouse is physiologically very similar to human. Also, there is a large genetic reservoir of potential models of human diseases that has been generated. In addition, high-resolution genetic and physical linkage maps are now available and the sequence of mouse genome will be ...
Kung, HF, Huang, JD
openaire   +2 more sources

The Assembly of the Human and Mouse Genomes

2002
Paired-read shotgun sequencing of a genome consists of randomly sampling segments of a fixed length, say 10,000 base pairs (10Kbp), and directly determining a “read” of 500 to 700bp at the two ends of each segment with an automated DNA sequencing instrument.
openaire   +1 more source

Human neutrophil development and functionality are enabled in a humanized mouse model

Proceedings of the National Academy of Sciences of the United States of America, 2022
Jackson Ruaidhrí, Luo Hongbo R, Bruscia Emanuela M   +2 more
exaly  

Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research

Journal of Virology, 2022
Leo Holguin, Liliana Echavarría, John C Burnett   +2 more
exaly  

Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions

Cell Reports Methods, 2022
Basma Benabdallah, Oanh Le, Massimiliano Paganelli   +2 more
exaly  

An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals

Drug Metabolism and Pharmacokinetics, 2022
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda   +2 more
exaly  

Emerging Preclinical Applications of Humanized Mouse Models in the Discovery and Validation of Novel Immunotherapeutics and Their Mechanisms of Action for Improved Cancer Treatment

Pharmaceutics, 2023
Isha Karnik, Zhisheng Her, Shu Hui Neo
exaly  

Benefits and limitations of humanized mouse models for human red blood cell-related disease research

Frontiers in Hematology, 2023
exaly  

Humanized Mouse Models of Clinical Disease

Annual Review of Pathology: Mechanisms of Disease, 2017
Nicole C Walsh, Sonal Jangalwe, Michael A Brehm   +2 more
exaly