Results 101 to 110 of about 37,460 (168)

Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration. [PDF]

, 2019
Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and ...
Barch, Mariya, Campioni, Matthew, Epstein, Irina, Finkbeiner, Steven, Javaherian, Ashkan, Linsley, Jeremy W, Mount, Elliot, Nowakowski, Tomasz J, Oza, Viral, Samsi, Siddharth, Schmunk, Galina, Tripathi, Atmiyata   +11 more
core  

Downregulation of huntingtin-associated protein 1 predicts poor prognosis in gastric cancer. [PDF]

World J Clin Oncol
Wang XY, Yang FH, Yuan ZY, Wang ZJ, Zhang HF, Xu ZH.   +5 more
europepmc   +1 more source

<i>Sida cordifolia</i> is efficacious in models of Huntington's disease by reducing ER stress. [PDF]

Front Mol Biosci
Simha PK, Mukherjee C, Kumar Gupta V, Bhatia K, Nagar P, Za AN, Godbole A, Sahu BS, Upadhyay SK.   +8 more
europepmc   +1 more source

Combination therapy of mitochondria-targeted antioxidants and polyphenols for early intervention in Huntington's disease. [PDF]

EXCLI J
Acharya A, Vishwas S, Singh SK.
europepmc   +1 more source

Evaluation of an Antisense Oligonucleotide Targeting CAG Repeats: A Patient-Customized Therapy Study for Huntington's Disease. [PDF]

Life (Basel)
Ocampo-Ortega SA, Sierra-Sanchez VM, Blancas-Napoles CM, González-Carteño A, Mera-Jiménez E, Macías-Pérez ME, Hernandez-Guerra A, Romero-Nava R, Huang F, Hong E, Villafaña S.   +10 more
europepmc   +1 more source

mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance. [PDF]

Elife
Stavrides P, Goulbourne CN, Peddy J, Huo C, Rao M, Khetarpal V, Marchionini DM, Nixon RA, Yang DS.   +8 more
europepmc   +1 more source

Untangling huntingtin's mysteries [PDF]

Nature Medicine, 2000
openaire   +2 more sources

The N17 domain of huntingtin as a multifaceted player in Huntington's disease. [PDF]

Front Mol Biosci
Cho H.
europepmc   +1 more source

Small striatal huntingtin inclusions in patients with motor neuron disease with reduced penetrance and intermediate HTT gene expansions. [PDF]

Hum Mol Genet
Roos AK, Stenvall E, Kockum ES, Grönlund KÅ, Alstermark H, Wuolikainen A, Andersen PM, Nordin A, Forsberg KME.   +8 more
europepmc   +1 more source

Isothiocyanates induce autophagy and inhibit protein synthesis in primary cells via modulation of AMPK-mTORC1-S6K1 signaling pathway, and protect against mutant huntingtin aggregation. [PDF]

Eur J Nutr
Brokowska J, Herman-Antosiewicz A, Hać A.   +2 more
europepmc   +1 more source