Results 161 to 170 of about 44,176 (282)

Targeting huntingtin [PDF]

Nature Structural & Molecular Biology, 2014
openaire   +1 more source

Allele-specific regulation of mutantHuntingtinby Wig1, a downstream target of p53 [PDF]

, 2016
Sun-Hong Kim, Neelam Shahani, Byoung-Il Bae, Juan I. Sbodio, Youjin Chung, Kazuhiro Nakaso, Bindu D. Paul, Akira Sawa   +7 more
openalex   +1 more source

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity

, 2015
Yuwei Yao, Xiaotian Cui, Ismael Al‐Ramahi, Xiaoli Sun, Bo Li, Jiapeng Hou, Marian DiFiglia, James Palacino, Zhi‐Ying Wu, Lixiang Ma, Juan Botas, Boxun Lu   +11 more
openalex   +1 more source

Mutant Huntingtin Promotes the Fibrillogenesis of Wild-type Huntingtin [PDF]

Journal of Biological Chemistry, 2003
Anne Busch, Sabine Engemann, Rudi Lurz, Hitoshi Okazawa, Hans Lehrach, Erich E. Wanker   +5 more
openaire   +1 more source

Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing

, 2022
Fang Li, Alex Mas Monteys, Alexandra Dürr, Megan S. Keiser, Congsheng Cheng, Akhil Harapanahalli, Pedro Gonzalez‐Alegre, Beverly L. Davidson, Kai Wang   +8 more
openalex   +1 more source

Huntingtin [PDF]

, 2019
openaire   +1 more source

Hunting out mutant huntingtin [PDF]

Nature Reviews Neuroscience, 2019
openaire   +2 more sources

AMT-130 gene therapy: a promising disease-modifying approach for Huntington's disease. [PDF]

Ann Med Surg (Lond)
Mwape C, Qureshi AA, Saeed MZ, Fatima A, Jamil A, Mahmood H, Batool A, Khan AM.   +7 more
europepmc   +1 more source

Discovery of sultam-containing small-molecule disruptors of the huntingtin–calmodulin protein–protein interaction

, 2022
N.J. Klus, K. Kapadia, P. McDonald, A. Roy, K.J. Frankowski, N.A. Muma, J. Aubé   +6 more
openalex   +1 more source

Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates. [PDF]

J Biol Chem
Lugo J, Xu H, Chen J, Khoshnan A, Langen R.   +4 more
europepmc   +1 more source