Results 141 to 150 of about 25,505 (239)
Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons
Traffic, Volume 27, Issue 2, June 2026.Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano +6 more
wiley +1 more source
, 2001 OBJECTIVESRecent data suggest that wild type huntingtin can protect against apoptosis in the testis of mice expressing full length huntingtin transgenes with expanded CAG repeats.
Rubinsztein, D.C. +4 more
core
, 2019 Attempts to test PAR binding of huntingtin purified with nickel or heparin.
Maiuri, Tamara +5 more
core +1 more source
Altered genes that directly interact with huntingtin.
, 2016 Altered genes that directly interact with huntingtin.
Andrew C. McCourt (3143664) +6 more
core +1 more source
Analyse der N-terminalen proteolytischen Prozessierung von Huntingtin [PDF]
, 2009 Chorea Huntington ist eine progressiv verlaufende neurodegenerative Erbkrankheit, die durch eine Expansion im Polyglutamin-Abschnitt des krankheitsassoziierten Proteins Huntingtin verursacht wird.
Jünemann, Katrin
core
Role of huntingtin phosphorylation at serine 421 in Huntington Disease
, 2007 Huntington Disease (HD) is a lethal neurodegenerative disorder that results from polyglutamine-expansion in the huntingtin protein. Despite the widespread tissue expression pattern of huntingtin, there is selective degeneration of specific neurons ...
Warby, Simon Christopher
core
Frontiers in NeuroscienceVPS13A disease and Huntington’s disease (HD) are two basal ganglia disorders that may be difficult to distinguish clinically because they have similar symptoms, neuropathological features, and cellular dysfunctions with selective degeneration of the ...
Esther García-García +27 more
doaj +1 more source
, 1998 The cellular and subcellular distribution of HAP1 was examined in rat brain by light and electron microscopic immunocytochemistry and subcellular fractionation.
Xiao-Jiang Li +5 more
core +1 more source
Navigating the neuronal recycling bin: Another look at huntingtin in coordinating autophagy
Autophagy ReportsNeurons, as post–mitotic and long–lived cells, rely heavily on autophagy to maintain cellular homoeostasis and ensure proper function. Huntingtin (HTT), a protein central to Huntington’s disease (HD), has emerged as a putative multifunctional regulator ...
Thomas J. Krzystek, Shermali Gunawardena
doaj +1 more source
Huntingtin can co-localize to vinculin-positive adhesion structures.
, 2019 Double-label immunofluorescence with anti-Huntingtin antibody Ab2527 (Green) and anti-Vinculin (Red). (a) In serum starved cells, Huntingtin immunoreactivity occurs along stress fibers leading into large Vinculin-positive adhesion plaques (top row ...
Ellen Sapp (4015658) +9 more
core +1 more source