Results 161 to 170 of about 19,992 (185)

Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin

Journal of Personalized Medicine, 2021
Andrea Ilari, Annarita Fiorillo, Gianni Colotti   +2 more
exaly  

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches

Brain Communications, 2022
Wenzhen Duan, Casandra Gomez Paredes, Georgina Osborne   +2 more
exaly  

Emerging Therapies for Huntington’s Disease – Focus on N-Terminal Huntingtin and Huntingtin Exon 1

Biologics: Targets and Therapy, 2022
M Leontien Van Der Bent, Astrid Valles, Melvin Evers   +2 more
exaly  

Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms

Brain Communications, 2021
Bridget Taxy, Wenzhen Duan, Georgina Osborne   +2 more
exaly  

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease

Cell, 2018
Weili Yang, Shihua Li, Huaqiang Yang
exaly  

Huntingtin: a single bait hooks many species

Current Opinion in Neurobiology, 1998
James Gusella, Marcy E Macdonald, M E Macdonald   +2 more
exaly  

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction

Biochemical and Biophysical Research Communications, 2006
Amit Mishra, Nobuyuki Nukina, Nihar Jana   +2 more
exaly  

Loss of normal huntingtin function: new developments in Huntington's disease research

Trends in Neurosciences, 2001
Elena Cattaneo, Simonetta Sipione, Squitieri F   +2 more
exaly  

Huntingtin toxicity

Trends in Molecular Medicine, 2001
openaire   +1 more source

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

Proceedings of the National Academy of Sciences of the United States of America, 2017
Hilal Lashuel, Elena Cattaneo, Squitieri F   +2 more
exaly