Results 171 to 180 of about 19,992 (185)

Potential function for the Huntingtin protein as a scaffold for selective autophagy

Proceedings of the National Academy of Sciences of the United States of America, 2014
David E Housman, Tamás Lukacsovich, Frédéric Saudou   +2 more
exaly  

Depletion of wild-type huntingtin in mouse models of neurologic diseases

Journal of Neurochemistry, 2003
Michael R Hayden, Elena Cattaneo, Blair R Leavitt   +2 more
exaly  

Imaging mutant huntingtin in vivo

Nature Reviews Drug Discovery, 2022
openaire   +2 more sources

A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation

Molecular Cell, 2018
Frédérique Rau, Alan Lowe, Helen R Saibil   +2 more
exaly  

Huntington's disease gene product, huntingtin, associates with microtubules in vitro

Molecular Brain Research, 1997
Nobuyuki Nukina
exaly  

Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model

Journal of Neurochemistry, 2011
Paolo Paganetti, Barbara Baldo
exaly  

The Benefits of Huntingtin

Science, 2001
openaire   +1 more source

<p>The effects of huntingtin-lowering: what do we know so far?</p>

Degenerative Neurological and Neuromuscular Disease, 2019
William Kaemmerer, Richard Grondin
exaly  

Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23

Proceedings of the National Academy of Sciences of the United States of America, 2019
Svitlana Yablonska, Nicolas Khattar, Vinitha Ganesan   +2 more
exaly  

Huntingtin inhibits caspase-3 activation

EMBO Journal, 2006
Michael R Hayden, Jeremy Van Raamsdonk, Blair R Leavitt   +2 more
exaly