Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin [published erratum appears in Hum Mol Genet 1999 May;8(5):943] [PDF]
, 1999 Gabriele Schilling
openalex +1 more source
New insight into genetic disease : the role of trinucleotide repeat expansions [PDF]
, 1995 The development of genetics in the last few decades is replete with surprise phenomena and new findings. One such phenomenon is the trinucleotide repeat expansion, a new type of mutation first discovered in 1991.
Cuschieri, Alfred
core
Restoration from polyglutamine toxicity after free electron laser irradiation of neuron-like cells [PDF]
, 2019 学位記番号 ...
Mohara, Miho +2 more
core
2008 Progress Report on Brain Research [PDF]
, 2008 Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder +3 more
core
Expression of Normal and Mutant Huntingtin in the Developing Brain [PDF]
, 1996 Pradeep G. Bhide +10 more
openalex +1 more source
, 2012 La maladie de Huntington (MH) est une maladie neurodégénérative héréditaire autosomique dominante. Elle résulte d’une expansion anormale de glutamines (polyQ) dans la partie N-terminale de la protéine huntingtine (HTT ; codé par HTT). La MH est caractérisée par la dysfonction et la mort de cellules neuronales dans le cerveau, entraînant l’apparition de
openaire +1 more source
Protein Aggregates and Polyglutamine Tracts In Neurodegenerative Disease [PDF]
, 2018 The incidence of neurodegenerative diseases such as Alzheimer\u27s Disease, Parkinson\u27s Disease, Huntington\u27s Disease and other Polyglutamine Diseases is projected to dramatically increase throughout the developed world, and yet the pathology of ...
Mack, John
core +1 more source
Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain [PDF]
, 1997 Veronica Colomer +8 more
openalex +1 more source
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]
, 2013 Brown, Euan R. +2 more
core +1 more source