Results 171 to 180 of about 44,176 (282)

Oleuropein enhances proteasomal activity and reduces mutant huntingtin-induced cytotoxicity [PDF]

Zih-Ning Huang, Sin-Yi Lee, Jie-Mao Chen, Zih-Ting Huang, Lu‐Shiun Her   +4 more
openalex   +1 more source

Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors [PDF]

, 2016
Yujin Kim, Fabian Hosp, Frédéric Frottin, Hui Ge, Matthias Mann, Manajit Hayer‐Hartl, F. Ulrich Hartl   +6 more
openalex   +1 more source

Perturbation of multiprotein complexes in skeletal muscle induces protective proteases in the CNS that degrade pathogenic proteins. [PDF]

NPJ Aging
Rai M, Baddeley HJE, Chuang CL, Platt A, Curley M, Finkelstein D, Demontis F.   +6 more
europepmc   +1 more source

Huntingtin Exon 1 Q16 And Q46 Pet32A Thioredoxin Tagged Expression And Purification 2018/04/09

, 2018
Rachel Harding, Mani Ravichandran, C.H. Arrowsmith, A.M. Edwards   +3 more
openalex   +1 more source

Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease. [PDF]

Brain Commun
Sanchez-Migallon P, Flores-Cuadrado A, Villanueva-Anguita P, Rabano A, Vaamonde J, Saiz-Sanchez D, Mohedano-Moriano A, Astillero-Lopez V, Soriano-Herrador C, Martinez-Marcos A, Ubeda-Banon I.   +10 more
europepmc   +1 more source

Huntingtin Nanobody Purification Using Osmotic Shock Cell Lysis – 2018/04/02

, 2018
Rachel Harding, Mani Ravichandran, C.H. Arrowsmith, A.M. Edwards   +3 more
openalex   +1 more source

Characterization of the Huntingtin gene promoter and Huntingtin transcriptional regulation

, 2015
Huntington’s disease (HD) is a late onset, neurological, autosomal dominant genetic disorder. Despite being associated to a defined genetic mutation within the huntingtin gene (HTT), little is known about its transcriptional regulation. HTT is expressed, at varying levels, throughout the body.
openaire   +1 more source

Overview of Huntington's Disease and Emerging Treatment Strategies: A Narrative Review. [PDF]

Cureus
Vega AJ, Hernandez GV, O'Malley PA, Robin CJ, Parra AN, Varrassi G, Shekoohi S, Kaye AD.   +7 more
europepmc   +1 more source

ROS-Specific Huntingtin Interactions: Mass spec analysis of MMS-treated mouse striatal cells

, 2018
Tamara Maiuri, Ray Truant
openalex   +1 more source

Corrigendum: The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function

Frontiers in Molecular Neuroscience, 2017
Wojciech J. Szlachcic, Kalina Wiatr, Marta Trzeciak, Marek Figlerowicz, Maciej Figiel   +4 more
doaj   +1 more source