Results 181 to 190 of about 5,553,804 (280)

Siah-1-interacting protein regulates mutated huntingtin protein aggregation in Huntington's disease models. [PDF]

Cell Biosci, 2022
Latoszek E, Wiweger M, Ludwiczak J, Dunin-Horkawicz S, Kuznicki J, Czeredys M.   +5 more
europepmc   +1 more source

N-alpha-acetylation of Huntingtin protein increases its propensity to aggregate. [PDF]

J Biol Chem, 2021
Gottlieb L, Guo L, Shorter J, Marmorstein R.   +3 more
europepmc   +1 more source

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein [PDF]

, 2003
Haibing Jiang, Frederick C. Nucifora, Christopher A. Ross, Donald Defranco   +3 more
openalex   +1 more source

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]

, 2013
Brown, Euan R., Idris, Mohammed M, Thorndyke, Michael C   +2 more
core   +1 more source

Huntington\u27s Disease--A Review [PDF]

, 2016
Huntington’s disease is degenerative and effects both cognitive and motor functioning, beginning in the 20s and continuing a decline for about two decades until death.
Dunn, Christen
core   +1 more source

The huntingtin protein in Huntington disease

, 2017
Huntingtin disease (HD) is an autosomal dominant inheritable disease that mainly affects the brain. HD is caused by expansion of a CAG repeat within exon 1 of the huntingtin gene giving rise to the expression of a mutant huntingtin protein with an elongated polyQ repeat at it's N-terminus.
openaire   +1 more source

Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington's Disease. [PDF]

J Huntingtons Dis, 2022
Podvin S, Rosenthal SB, Poon W, Wei E, Fisch KM, Hook V.   +5 more
europepmc   +1 more source

A Protein Interaction Network Links GIT1, an Enhancer of Huntingtin Aggregation, to Huntington's Disease [PDF]

, 2004
Heike Goehler, Maciej Łałowski, Ulrich Stelzl, Stephanie Waelter, Martin Stroedicke, Uwe Worm, Anja Droege, Katrin S. Lindenberg, Maria Knoblich, Christian Haenig, Martin Herbst, Jaana Suopanki, Eberhard Scherzinger, Claudia Abraham, Bianca Bauer, Renate Hasenbank, Anja Fritzsche, Andreas H. Ludewig, K. Buessow, Sarah H Coleman, Claire‐Anne Gutekunst, G. Bernhard Landwehrmeyer, Hans Lehrach, Erich E. Wanker   +23 more
openalex   +1 more source

Fighting the Huntington's Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies. [PDF]

Int J Mol Sci, 2022
Riccardi C, D'Aria F, Digilio FA, Carillo MR, Amato J, Fasano D, De Rosa L, Paladino S, Melone MAB, Montesarchio D, Giancola C.   +10 more
europepmc   +1 more source

Huntingtin Interacting Protein 1 (HIP1) Regulates Clathrin Assembly through Direct Binding to the Regulatory Region of the Clathrin Light Chain [PDF]

, 2004
Valérie Legendre‐Guillemin, Martina Metzler, Jean‐François Lemaire, Jacynthe Philie, Lu Gan, Michael R. Hayden, Peter S. McPherson   +6 more
openalex   +1 more source