Results 171 to 180 of about 6,546,213 (228)

Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays. [PDF]

PLoS One, 2017
Hensman Moss DJ, Robertson N, Farmer R, Scahill RI, Haider S, Tessari MA, Flynn G, Fischer DF, Wild EJ, Macdonald D, Tabrizi SJ.   +10 more
europepmc   +1 more source

Juvenile Huntington's Disease Skin Fibroblasts Respond with Elevated Parkin Level and Increased Proteasome Activity as a Potential Mechanism to Counterbalance the Pathological Consequences of Mutant Huntingtin Protein. [PDF]

Int J Mol Sci, 2019
Aladdin A, Király R, Boto P, Regdon Z, Tar K.   +4 more
europepmc   +1 more source

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models. [PDF]

J Huntingtons Dis, 2018
Franich NR, Basso M, André EA, Ochaba J, Kumar A, Thein S, Fote G, Kachemov M, Lau AL, Yeung SY, Osmand A, Zeitlin SO, Ratan RR, Thompson LM, Steffan JS.   +14 more
europepmc   +1 more source

Striatal Neuron Excitability Is Regulated by Huntingtin in the Adult Brain. [PDF]

eNeuro
Barron JC, Greenland ML, Carew SJ, Ashrafganjoie F, Hurley EP, Kennedy CM, Nafar F, Moore CS, Parsons MP.   +8 more
europepmc   +1 more source

Lipid Composition Drives Mutant Huntingtin Dimerization and Membrane Association: Insights from Computational Simulations. [PDF]

Molecules
Nicoara C, Criscuolo E, De Cristofaro A, Fezza F, Maccarrone M.   +4 more
europepmc   +1 more source

Data-driven model reveals increased stability of CAG-expanded huntingtin RNA due to MID1 binding. [PDF]

PLoS Comput Biol
Liu Y, Reisbitzer A, Dorešić D, Hasenauer J, Krauß S, Tchumatchenko T.   +5 more
europepmc   +1 more source

Molecular features of a Huntington's disease knock-in minipig. [PDF]

Dis Model Mech
Kolesnikova A, Sathasivam K, Tusi SK, Landles C, Osborne GF, Kovalenko M, Gillis T, Kamenná E, Sekáč D, Nguyen DT, Valeková I, Juhás Š, Juhásová J, Levinská B, Baxa M, Motlík J, Klíma J, Howland D, Wheeler VC, Bates GP, Ellederova Z.   +20 more
europepmc   +1 more source

Genetic suppressor of autophagy defects in huntingtin null cells identified using a mutagenesis screen in Dictyostelium discoideum. [PDF]

BMC Mol Cell Biol
Cuoco L, Gill SE, Francois L, Souders S, DeMasi C, Moore JR, Chain FJJ.   +6 more
europepmc   +1 more source

SQSTM1/p62 UFMylation Enhances Autophagic Clearance of Pathogenic Mutant Huntingtin. [PDF]

Int J Biol Sci
Wang X, Lv X, Jiang H, Zhu W, Cao L, Zhou L, Lin F, Deng R, Hu LF, Ma J, Li JB, Xu G.   +11 more
europepmc   +1 more source

Lipid composition controls the huntingtin exon 1 membrane-association and differentially modulates its flanking regions' dynamics. [PDF]

Protein Sci
Sousa T, Damas G, Coutinho A, Bernardes N, Azevedo A, Prieto M, Melo AM.   +6 more
europepmc   +1 more source