Results 161 to 170 of about 6,546,213 (228)

A method for the analysis of the oligomerization profile of the Huntington's disease-associated, aggregation-prone mutant huntingtin protein by isopycnic ultracentrifugation. [PDF]

Front Mol Biosci
Bonavita R, Di Martino R, Cortone G, Prodomo A, Di Gennaro M, Scerra G, Panico V, Nuzzo S, Salvatore M, Williams SV, Vitale F, Caporaso MG, D'Agostino M, Pisani FM, Fleming A, Renna M.   +15 more
europepmc   +1 more source

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis

Cell Cycle, 2012
T. Ratovitski, E. Chighladze, N. Arbez, T. Boronina, Shelley M Herbrich, R. Cole, C. Ross   +6 more
semanticscholar   +1 more source

Mutant huntingtin protein induces MLH1 degradation, DNA hyperexcision, and cGAS-STING-dependent apoptosis. [PDF]

Proc Natl Acad Sci U S A
Sun X, Liu L, Wu C, Li X, Guo J, Zhang J, Guan J, Wang N, Gu L, Yang XW, Li GM.   +10 more
europepmc   +1 more source

Nucleation Inhibition of Huntingtin Protein (htt) by Polyproline PPII Helices: A Potential Interaction with the N-Terminal α-Helical Region of Htt. [PDF]

Biochemistry, 2020
Arndt JR, Chaibva M, Beasley M, Kiani Karanji A, Ghassabi Kondalaji S, Khakinejad M, Sarver O, Legleiter J, Valentine SJ.   +8 more
europepmc   +1 more source

High Levels of Mutant Huntingtin Protein in Tear Fluid From Huntington's Disease Gene Expansion Carriers. [PDF]

J Mov Disord
Gijs M, Jorna N, Datson N, Beekman C, Dansokho C, Weiss A, Linden DEJ, Oosterloo M.   +7 more
europepmc   +1 more source

Expression of Human Mutant Huntingtin Protein in Drosophila Hemocytes Impairs Immune Responses. [PDF]

Front Immunol, 2019
Lin YH, Maaroufi HO, Ibrahim E, Kucerova L, Zurovec M.   +4 more
europepmc   +1 more source

Mutant Huntingtin Protein: A Substrate for Transglutaminase 1, 2, and 3

Journal of Neuropathology and Experimental Neurology, 2005
G. M. Zainelli, Nichole L. Dudek, C. Ross, Soo‐Youl Kim, N. Muma   +4 more
semanticscholar   +1 more source

Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease. [PDF]

Neurosci Bull, 2019
Yang W, Xie J, Qiang Q, Li L, Lin X, Ren Y, Ren W, Liu Q, Zhou G, Wei W, Saiyin H, Ma L.   +11 more
europepmc   +1 more source

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.

Human Molecular Genetics, 2002
Edmond Y. W. Chan, R. Luthi-Carter, A. Strand, S. Solano, S. A. Hanson, Molly M. DeJohn, C. Kooperberg, Kathryn O. Chase, M. Difiglia, A. Young, B. Leavitt, J. Cha, N. Aronin, M. Hayden, J. Olson   +14 more
semanticscholar   +1 more source

Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay. [PDF]

eNeuro, 2018
Baldo B, Sajjad MU, Cheong RY, Bigarreau J, Vijayvargia R, McLean C, Perrier AL, Seong IS, Halliday G, Petersén Å, Kirik D.   +10 more
europepmc   +1 more source