Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration. [PDF]
, 2019 Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and ...
Barch, Mariya +11 more
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Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates. [PDF]
Mol Biol Cell, 2022 Bae D +5 more
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Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers. [PDF]
Front Mol Biosci, 2023 Khaled M, Strodel B, Sayyed-Ahmad A.
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Screening Conditions For Electron Microscopy Of Full-Length Huntingtin Protein Samples
, 2016 Rachel Harding +4 more
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The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. [PDF]
Hum Mol Genet, 2023 Bonavita R +12 more
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Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington’s disease [PDF]
, 2018 Xiao Zhou +10 more
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Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. [PDF]
Cell Syst, 2022 Greco TM +12 more
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Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression. [PDF]
Pharmaceutics, 2021 Chen XQ +9 more
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A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy [PDF]
, 2008 Randy Singh Atwal, Ray Truant
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