Results 201 to 210 of about 5,553,804 (280)

Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model

open access: yesNeurobiology of Disease, 2005
Neuronal cell death in HD is believed to be largely a dominant cell-autonomous effect of the mutant huntingtin protein. We previously developed an inducible PC12 cell model which expresses an N-terminal huntingtin fragment with an expanded poly Q repeat (
Wenfei Wang   +5 more
doaj  

NMDA Receptor Function and NMDA Receptor-Dependent Phosphorylation of Huntingtin Is Altered by the Endocytic Protein HIP1 [PDF]

open access: hybrid, 2007
Martina Metzler   +12 more
openalex   +1 more source

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice [PDF]

open access: bronze, 2008
Guoqing Sheng   +9 more
openalex   +1 more source

Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein [PDF]

open access: hybrid, 2011
Jonathan H. Fox   +14 more
openalex   +3 more sources

Use of a Cryptic Splice Site for the Expression of Huntingtin Interacting Protein 1 in Select Normal and Neoplastic Tissues [PDF]

open access: bronze, 2008
Chiron W. Graves   +6 more
openalex   +1 more source

Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2) [PDF]

open access: green, 2009
Randall C. Wilson   +5 more
openalex   +1 more source

Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1

open access: bronze, 2003
Tie-Shan Tang   +7 more
openalex   +1 more source

Potent inhibitors of Huntingtin protein aggregation in a cell-based assay [PDF]

open access: green, 2009
Alison Rinderspacher   +15 more
openalex   +1 more source

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