Neuronal cell death in HD is believed to be largely a dominant cell-autonomous effect of the mutant huntingtin protein. We previously developed an inducible PC12 cell model which expresses an N-terminal huntingtin fragment with an expanded poly Q repeat (
Wenfei Wang+5 more
doaj
NMDA Receptor Function and NMDA Receptor-Dependent Phosphorylation of Huntingtin Is Altered by the Endocytic Protein HIP1 [PDF]
Martina Metzler+12 more
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Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice [PDF]
Guoqing Sheng+9 more
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The role of j proteins in mutant huntingtin aggregation
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openaire +2 more sources
Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein [PDF]
Jonathan H. Fox+14 more
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Use of a Cryptic Splice Site for the Expression of Huntingtin Interacting Protein 1 in Select Normal and Neoplastic Tissues [PDF]
Chiron W. Graves+6 more
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Two Distantly Spaced Basic Patches in the Flexible Domain of Huntingtin-Interacting Protein 1 (HIP1) Are Essential for the Binding of Clathrin Light Chain [PDF]
Joel A. Ybe+4 more
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Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2) [PDF]
Randall C. Wilson+5 more
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Potent inhibitors of Huntingtin protein aggregation in a cell-based assay [PDF]
Alison Rinderspacher+15 more
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