Results 201 to 210 of about 37,609 (272)

I'll Be Dammed: Efficiency and Cost‐Analysis of a Rehabilitated Prehispanic Dam in the Andes

open access: yesGeoarchaeology, Volume 41, Issue 4, July/August 2026.
ABSTRACT Within archaeology there is a growing shift away from the purely aesthetic towards making the past relevant to present and future needs and demands. The Past Water Futures project charts the impact of ancient dam rehabilitation on climate change‐induced water scarcity in the North Central Andes.
Kevin Lane   +5 more
wiley   +1 more source

Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers

open access: yesMedComm, Volume 7, Issue 7, July 2026.
This schematic illustrates the hierarchical and interconnected nature of the primary molecular hallmarks of aging. The progression of aging is driven by a convergence of intrinsic molecular insults. Within the nucleus, genomic instability and telomere attrition trigger persistent DDR, accompanied by extensive epigenetic alterations.
Guowei Cai   +10 more
wiley   +1 more source

Correction: F2,6BP restores mitochondrial genome integrity in Huntington's disease. [PDF]

open access: yesJ Biol Chem
Chakraborty A   +13 more
europepmc   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

open access: yesPROTEOMICS, Volume 26, Issue 7, Page 146-157, July 2026.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam   +4 more
wiley   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

open access: yesPhytotherapy Research, Volume 40, Issue 7, Page 4588-4610, July 2026.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo   +11 more
wiley   +1 more source

Gastroscopic Evaluation of Gastric Mucosa in Horses Treated With Flunixin Meglumine or High‐Dose Firocoxib: A Descriptive Pilot Study

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
In this descriptive pilot study, short‐term (5‐day) high‐dose firocoxib (1.0 mg/kg) was not associated with detectable gastric mucosal injury in horses. Due to non‐randomised design and small sample size (n = 5/group), no causal conclusions can be drawn. Findings are hypothesis‐generating and require confirmation in adequately powered trials.
Renato Abrantes de Oliveira   +3 more
wiley   +1 more source

Engineering Extracellular Vesicles for Anti‐Aging Therapy: Mechanisms, Applications, and Perspectives

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang   +6 more
wiley   +1 more source

Development and Validation of a Brief Fall Questionnaire (FALL-HD) for Patients with Huntington's Disease. [PDF]

open access: yesMov Disord Clin Pract
Kaur J   +7 more
europepmc   +1 more source

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