Results 121 to 130 of about 9,201,564 (391)
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity [PDF]
, 2015 Assemblies of huntingtin (HTT) fragments with expanded polyglutamine (polyQ) tracts are a pathological hallmark of Huntington's disease (HD). The molecular mechanisms by which these structures are formed and cause neuronal dysfunction and toxicity are ...
Andrade-Navarro, Miguel A. +24 more
core +2 more sources
Animal Research and One Health, EarlyView.This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou +4 more
wiley +1 more source
Scientific Reports, 2017 Huntington disease is a fatal neurodegenerative disorder caused by a CAG repeat expansion in the gene encoding the huntingtin protein. Expression of the mutant protein disrupts various intracellular pathways and impairs overall cell function.
Elisabeth Singer +8 more
doaj +1 more source
Enfermedad de Huntington: estado del arte [PDF]
, 2014 La enfermedad de Huntington es un desorden monogenético autosómico dominante, que genera un trastorno neurodegenerativo caracterizado por la pérdida de neuronas en diferentes partes del cerebro.
Rodas Sepúlveda, Carlos Daniel +1 more
core
Longitudinal Beta-Binomial Modeling using GEE for Over-Dispersed Binomial Data [PDF]
, 2016 Longitudinal binomial data are frequently generated from multiple questionnaires and assessments in various scientific settings for which the binomial data are often overdispersed.
Long, Jeffrey D. +2 more
core +1 more source
Frontiers in Neuroscience, 2018 In recent years, several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and Huntington's disease (HD).
Sandra Franco-Iborra, M. Vila, C. Perier
semanticscholar +1 more source
A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education
Clinical Anatomy, EarlyView.ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley +4 more
wiley +1 more source
Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]
, 2018 Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg +10 more
core +1 more source
Chemistry &Biodiversity, EarlyView.Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández +3 more
wiley +1 more source
The achievement and prospect of deep brain stimulation for the treatment of movement disorders
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Deep brain stimulation (DBS) was first used in the treatment of essential tremor in 1987, and later used in the treatment of advanced Parkinson's disease (PD), drug⁃refractory dystonia, other types of tremor and Tourette's syndrome, which can reduce the ...
Chao⁃shi NIU, Chi XIONG
doaj