Results 131 to 140 of about 9,130,139 (414)

Feeding and management practices for racehorses in Turkey [PDF]

open access: yes, 2018
The aim of this study was to gather information on feeding practices, and to identify nutrient imbalances of racehorses in Turkey. 134 racehorses who visited the TJK (Turkish Jockey Club) Racecourse Equine Hospital in Istanbul were referred for ...
Huntington, Peter   +3 more
core   +1 more source

Mutant Huntingtin Affects Diabetes and Alzheimer’s Markers in Human and Cell Models of Huntington’s Disease

open access: yesCells, 2019
A higher incidence of diabetes was observed among family members of individuals affected by Huntington’s Disease with no follow-up studies investigating the genetic nature of the observation.
Gepoliano Chaves   +2 more
doaj   +1 more source

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease

open access: yesScience Translational Medicine, 2018
Mutant huntingtin and neurofilament in biofluids may have prognostic potential in Huntington’s disease. Improving Huntington’s disease detection Early detection of Huntington’s disease (HD) could help the development of effective therapeutic strategies ...
L. Byrne   +12 more
semanticscholar   +1 more source

Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes [PDF]

open access: yes, 2018
Huntington disease (HD) is an inherited neurodegenerative disease caused by the expansion beyond a critical threshold of a polyglutamine (polyQ) tract near the N-terminus of the huntingtin (htt) protein. Expanded polyQ promotes the formation of a variety
Campbell, Warren A.   +5 more
core   +4 more sources

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

open access: yesBioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study [PDF]

open access: yes, 2007
BACKGROUND : Animal data and postmortem studies suggest a role of oxidative stress in the Huntington's disease (HD), but in vivo human studies have been scarce.
Babić, Tomislav   +5 more
core   +1 more source

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

open access: yesBioEssays, EarlyView.
Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler   +2 more
wiley   +1 more source

The achievement and prospect of deep brain stimulation for the treatment of movement disorders

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Deep brain stimulation (DBS) was first used in the treatment of essential tremor in 1987, and later used in the treatment of advanced Parkinson's disease (PD), drug⁃refractory dystonia, other types of tremor and Tourette's syndrome, which can reduce the ...
Chao⁃shi NIU, Chi XIONG
doaj  

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease

open access: yesFrontiers in Neuroscience, 2018
In recent years, several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and Huntington's disease (HD).
Sandra Franco-Iborra, M. Vila, C. Perier
semanticscholar   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

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