Results 171 to 180 of about 9,201,564 (391)

Clinical and genetic study of a juvenile⁃onset Huntington disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Background Huntington's disease (HD) is an autosomal dominant hereditary progressive neurodegenerative disorder with a distinct phenotype characterized by chorea, dementia, cognitive and affective impairment.
Ying HAO, Yuan⁃yuan CHEN, Wei⁃hong GU, Guo⁃xiang WANG, Hui⁃zi MA, Li⁃lin LI, Kang WANG, Miao JIN, Xiao⁃hui DUAN   +8 more
doaj  

Diagnosis of Huntington Disease [PDF]

, 2003
Russell L. Margolis, Christopher A. Ross
openalex   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

AAV-Mediated gene delivery of BDNF or GDNF is neuroprotective in a model of huntington disease [PDF]

, 2004
Adrian P. Kells, Dahna M. Fong, Mike Dragunow, Matthew J. During, Deborah Young, Bronwen Connor   +5 more
openalex   +1 more source

Rodent genetic models of Huntington disease

Neurobiology of Disease, 2008
Huntington disease (HD) is a dominantly inherited human neurodegenerative disorder characterized by motor deficits, cognitive impairment, and psychiatric symptoms leading to inexorable decline and death.
Mary Y. Heng, Peter J. Detloff, Roger L. Albin   +2 more
doaj  

Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder in Huntington Disease Patient with Improvement in Neuropsychiatric and Movement Symptoms: A Case Report

Case Reports in Neurology
Introduction: Huntington disease (HD) is a progressive disorder characterized by significant neurodegeneration that results in severe neuropsychiatric symptoms and disordered movement.
Cheyenne Rahn, Kris Peterson, Elizabeth Lamb   +2 more
doaj   +1 more source

Two Centuries of Mortality in Ten Large Families with Huntington Disease

, 1999
E.T.M. Hille, Sabine Siesling, M Vegter-van der Vlis, Jan P. Vandenbroucke, Raymund A.C. Roos, Frits R. Rosendaa   +5 more
openalex   +1 more source

The CAG repeat at the Huntington disease gene in the Portuguese population: insights into its dynamics and to the origin of the mutation [PDF]

, 2005
Maria do Carmo Costa, Paula Magalhães, Laura Guimarães, Patrı́cia Maciel, Jorge Sequeiros, Alda Sousa   +5 more
openalex   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head, Jessica D. Ewald, Niladri Basu   +2 more
wiley   +1 more source

Functional Connectivity and Volumetrics Improve Outcome Prediction for Deep Brain Stimulation in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) targeting the subthalamic nucleus (STN) can effectively treat motor symptoms of Parkinson's disease (PD). However, optimal patient selection remains challenging due to the inadequacy of outcome predictors.
John R. Younce, Scott A. Norris, Mwiza Ushe, Joel S. Perlmutter   +3 more
wiley   +1 more source