Results 171 to 180 of about 9,130,139 (414)
Multiscale Fluctuation-based Dispersion Entropy and its Applications to Neurological Diseases [PDF]
Fluctuation-based dispersion entropy (FDispEn) is a new approach to estimate the dynamical variability of the fluctuations of signals. It is based on Shannon entropy and fluctuation-based dispersion patterns. To quantify the physiological dynamics over multiple time scales, multiscale FDispEn (MFDE) is developed in this article.
arxiv
A Recurrent Expansion of a Maternal Allele with 36 CAG Repeats Causes Huntington Disease in Two Sisters [PDF]
Franco Laccone, Wilhelm Christian
openalex +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang+3 more
wiley +1 more source
Global prevalence of neurological disorders such as Parkinson's disease, Alzheimer's disease, epilepsy, and multiple sclerosis is steadily increasing, but, there is still no effective delivery system to deliver therapeutic amounts of drug into the ...
Sara Assadpour+2 more
doaj
Polymorphisms in the CAG repeat – a source of error in Huntington disease DNA testing [PDF]
Shaoqing Yu+3 more
openalex +1 more source
Psychological impact of news of genetic risk for Huntington disease [PDF]
Mardi J. Horowitz+5 more
openalex +1 more source
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang+4 more
wiley +1 more source
Get the News Out Loudly and Quickly: Modeling the Influence of the Media on Limiting Infectious Disease Outbreaks [PDF]
During outbreaks of serious infectious diseases many individuals closely follow media reports of the outbreak and take steps, including self-isolation, to protect themselves from infection and possibly death. Self-isolation can take many forms including restricting local and long-distance travel, using face masks, and choosing to receive a vaccine.
arxiv
Long-Term Cortical Atrophy after Excitotoxic Striatal Lesion: Effects of Intrastriatal Fetal-Striatum Grafts and Implications for Huntington Disease [PDF]
Ana Muñoz+4 more
openalex +1 more source
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka+5 more
wiley +1 more source